Gene Symbol |
NDUFC2
|
Entrez Gene |
4718
|
Alt Symbol |
B14.5b, CI-B14.5b, HLC-1, NADHDH2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
|
Other Description |
NADH dehydrogenase [ubiquinone] 1 subunit C2|NADH-ubiquinone oxidoreductase subunit B14.5b|complex I subunit B14.5b|complex I-B14.5b|human lung cancer oncogene 1 protein
|
Swissprots |
E9PNU8 O95298 E9PRB2 Q9UBJ9 Q549M5 Q6FIH8
|
Accessions |
EAW75046 EAW75047 O95298 AF070652 AAD20958 AF087659 AAD09754 AF087899 AAP97198 AF369951 AAM21294 AF369952 AAM21295 AK022785 AK023013 AK098173 AL050278 CAB43379 AM392713 CAL37591 BC007323 AAH07323 BE740715 BX281908 CA414824 CR533448 CAG38479 NM_001204054 NP_001190983 NM_001204055 NP_001190984 NM_004549 NP_004540
|
Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
|
Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|