Gene Symbol | NDUFC2 |
---|---|
Entrez Gene | 4718 |
Alt Symbol | B14.5b, CI-B14.5b, HLC-1, NADHDH2 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 subunit C2|NADH-ubiquinone oxidoreductase subunit B14.5b|complex I subunit B14.5b|complex I-B14.5b|human lung cancer oncogene 1 protein |
Swissprots | E9PNU8 O95298 E9PRB2 Q9UBJ9 Q549M5 Q6FIH8 |
Accessions | EAW75046 EAW75047 O95298 AF070652 AAD20958 AF087659 AAD09754 AF087899 AAP97198 AF369951 AAM21294 AF369952 AAM21295 AK022785 AK023013 AK098173 AL050278 CAB43379 AM392713 CAL37591 BC007323 AAH07323 BE740715 BX281908 CA414824 CR533448 CAG38479 NM_001204054 NP_001190983 NM_001204055 NP_001190984 NM_004549 NP_004540 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFC2 CRISPR/Cas9 KO Plasmid (h) - sc-416902 from Santa Cruz Biotechnology
|
||||||||
NDUFC2 HDR Plasmid (h) - sc-416902-HDR from Santa Cruz Biotechnology
|
||||||||
NDUFC2 Double Nickase Plasmid (h) - sc-416902-NIC from Santa Cruz Biotechnology
|
||||||||
NDUFC2 Double Nickase Plasmid (h2) - sc-416902-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NDUFC2 CRISPR Activation Plasmid (h) - sc-416902-ACT from Santa Cruz Biotechnology
|
||||||||
NDUFC2 CRISPR Activation Plasmid (h2) - sc-416902-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NDUFC2 Lentiviral Activation Particles (h) - sc-416902-LAC from Santa Cruz Biotechnology
|
||||||||
NDUFC2 Lentiviral Activation Particles (h2) - sc-416902-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NDUFC2 siRNA (h) - sc-96468 from Santa Cruz Biotechnology
|
||||||||
NDUFC2 shRNA Plasmid (h) - sc-96468-SH from Santa Cruz Biotechnology
|
||||||||
NDUFC2 shRNA (h) Lentiviral Particles - sc-96468-V from Santa Cruz Biotechnology
|
||||||||
NDUFC2 RNAi - H00004718-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU079111 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15165 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15165 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR10119 from Sigma-Aldrich
|
||||||||
NDUFC2 siRNA (Human) - CRH3132 from Cohesion Biosciences
|
||||||||
shRNA set against Human NDUFC2 (NM_004549.5) - SHH350828 from Creative biogene
|
||||||||
Human NDUFC2 siRNA - orb263634 from Biorbyt
|
||||||||
NDUFC2 shRNA Plasmid (Human) - CHH3132 from Cohesion Biosciences
|
||||||||
NDUFC2 miRNA 3'UTR clone - MiUTR3H-06312 from Creative biogene
|