| Gene Symbol | HAGH |
|---|---|
| Entrez Gene | 3029 |
| Alt Symbol | GLO2, GLX2, GLXII, HAGH1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | hydroxyacylglutathione hydrolase |
| Other Description | glx II|glyoxalase II|hydroxyacylglutathione hydrolase, mitochondrial|hydroxyacylglutathione hydroxylase |
| Swissprots | A8K290 E7EN93 B4DP33 B4DRA7 Q16775 |
| Accessions | AAK61294 EAW85609 EAW85610 EAW85611 Q16775 AK054943 AK290155 BAF82844 AK298174 BAG60445 AK299173 BAG61219 AK299993 BAG61813 AK308825 AY576804 BC000840 AAH00840 BC002627 AAH02627 BG703401 BI758286 BU176541 DB502986 DQ891220 ABM82146 DQ891221 ABM82147 DQ894403 ABM85329 DR006636 EU176259 ABW03710 X90999 CAA62483 XM_011522469 XP_011520771 XM_011522470 XP_011520772 NM_001040427 NP_001035517 NM_001286249 NP_001273178 NM_005326 NP_005317 |
| Function | Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid. |
| Subcellular Location | Isoform 1: Mitochondrion matrix. |
| Tissue Specificity | Expressed in liver and kidney. {ECO:0000269|PubMed:15117945}. |
| Top Pathways | Pyruvate metabolism |