Gene Symbol |
Sh2b3
|
Entrez Gene |
58838
|
Alt Symbol |
Lnk
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
SH2B adaptor protein 3
|
Other Description |
SH2B adapter protein 3|linker of T-cell receptor pathways|lymphocyte adapter protein|lymphocyte-specific adapter protein Lnk|signal transduction protein Lnk
|
Swissprots |
P50745
|
Accessions |
EDM13717 P50745 JX215366 AFP87272 U24652 AAC52348 U24653 AAC52349 U24654 AAC52350 U24655 AAC52351 NM_031621 NP_113809
|
Function |
Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase.
|
Tissue Specificity |
Preferentially expressed by lymphocytes in lymph node and spleen.
|
Top Pathways |
Neurotrophin signaling pathway
|