| Gene Symbol |
GNG10
|
| Entrez Gene |
2790
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma 10
|
| Other Description |
guanine nucleotide binding protein 10|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
|
| Swissprots |
P50151 Q3B7K2 Q4VC27
|
| Accessions |
EAW59079 EAW59080 EAW59083 EAW59087 P50151 AF493877 AAM12591 AW583403 BC010384 AAH10384 BC015206 BC016319 AAH16319 BC072671 AAH72671 BC107574 AAI07575 BG708408 DB504443 HQ447946 ADQ32430 U31383 AAC50205 NM_001017998 NP_001017998 NM_001198664 NP_001185593
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Tissue Specificity |
Abundantly and ubiquitously expressed.
|
| Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|
![Western Blot: GNG10 Overexpression Lysate (Adult Normal) [NBL1-11170] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GNG10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7996_GNG10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11170-img0002.jpg)