Gene Symbol | ETV7 |
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Entrez Gene | 51513 |
Alt Symbol | TEL-2, TEL2, TELB |
Species | Human |
Gene Type | protein-coding |
Description | ets variant 7 |
Other Description | ETS translocation variant 7|ETS-related protein Tel2|Ets transcription factor TEL-2b|TEL2 oncogene|ets variant gene 7 (TEL2 oncogene)|tel-related Ets factor|transcription factor ETV7 |
Swissprots | Q9Y604 Q5R3L4 Q9Y603 Q9NZR8 Q9NZ65 Q5R3L3 Q9NZ68 Q9UNJ7 Q9Y5K4 B4DVB6 Q9NZ66 B3KVC2 B4E1G4 |
Accessions | CCW44093 EAX03885 EAX03886 EAX03887 EAX03888 EAX03889 EAX03890 Q9Y603 AF116508 AAD43250 AF116509 AAD43251 AF116510 AAD43252 AF147782 AAD33989 AF175387 AAF25007 AF218235 AAF28350 AF218365 AAF44742 AF218366 AAF44743 AJ276205 CAC17012 AK026144 AK122796 BAG53734 AK223424 BAD97144 AK301011 BAG62628 AK303829 BAG64776 BC035853 AAH35853 EU446843 ABZ92372 XM_011514659 XP_011512961 XM_011514660 XP_011512962 NM_001207035 NP_001193964 NM_001207036 NP_001193965 NM_001207037 NP_001193966 NM_001207038 NP_001193967 NM_001207039 NP_001193968 NM_001207040 NP_001193969 NM_001207041 NP_001193970 NM_016135 NP_057219 |
Function | Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in hematopoietic tissues. |
Top Pathways | Transcriptional misregulation in cancer, Dorso-ventral axis formation |
TEL2 CRISPR/Cas9 KO Plasmid (h) - sc-405502 from Santa Cruz Biotechnology
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TEL2 HDR Plasmid (h) - sc-405502-HDR from Santa Cruz Biotechnology
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TEL2 Double Nickase Plasmid (h) - sc-405502-NIC from Santa Cruz Biotechnology
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TEL2 Double Nickase Plasmid (h2) - sc-405502-NIC-2 from Santa Cruz Biotechnology
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TEL2 CRISPR Activation Plasmid (h) - sc-405502-ACT from Santa Cruz Biotechnology
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TEL2 CRISPR Activation Plasmid (h2) - sc-405502-ACT-2 from Santa Cruz Biotechnology
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TEL2 Lentiviral Activation Particles (h) - sc-405502-LAC from Santa Cruz Biotechnology
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TEL2 Lentiviral Activation Particles (h2) - sc-405502-LAC-2 from Santa Cruz Biotechnology
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TEL2 siRNA (h) - sc-95523 from Santa Cruz Biotechnology
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TEL2 shRNA Plasmid (h) - sc-95523-SH from Santa Cruz Biotechnology
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TEL2 shRNA (h) Lentiviral Particles - sc-95523-V from Santa Cruz Biotechnology
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ETV7 RNAi - H00051513-R01 from Novus Biologicals
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MISSION® esiRNA - EHU079741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8016 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8016 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04733 from Sigma-Aldrich
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ETV7 siRNA (Human) - CRH9803 from Cohesion Biosciences
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ETV7 - MBS8230929 from MyBioSource
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shRNA set against Human ETV7 (NM_016135.3) - SHH287753 from Creative biogene
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ETV7 shRNA Plasmid (Human) - CHH9803 from Cohesion Biosciences
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ETV7 miRNA 3'UTR clone - MiUTR3H-07518 from Creative biogene
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