Gene Symbol | UBE4A |
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Entrez Gene | 9354 |
Alt Symbol | E4, UBOX2, UFD2 |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitination factor E4A |
Other Description | ubiquitin conjugation factor E4 A|ubiquitination factor E4A (UFD2 homolog, yeast) |
Swissprots | B0YJB6 Q7Z639 Q2M1H0 Q14139 Q6P5T4 |
Accessions | ACA06094 CCQ43280 EAW67371 EAW67372 Q14139 AF087968 AK296369 BAG59044 AK302328 BAH13676 AK307737 AL713515 AW021567 AW290969 BC010938 BC030973 AAH30973 BC039240 BC052643 AAH52643 BC062695 AAH62695 BC111417 AAI11418 BC112367 AAI12368 BU167020 D50916 BAA09475 DB068702 NM_001204077 NP_001191006 NM_004788 NP_004779 |
Function | Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates. {ECO:0000250|UniProtKB:E9Q735, ECO:0000250|UniProtKB:P54860}. |
Subcellular Location | Cytoplasm {ECO:0000250|UniProtKB:E9Q735}. |
Top Pathways | Ubiquitin mediated proteolysis |
E4 / UBE4A Antibody Blocking Peptide - LS-E3491 from LifeSpan Bioscience
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E4 / UBE4A Antibody Blocking Peptide - LS-E6858 from LifeSpan Bioscience
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E4 / UBE4A Antibody Blocking Peptide - LS-E15842 from LifeSpan Bioscience
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UBE4A Peptide - P0880 from Novus Biologicals
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UBE4A-Antibody-Center-Blocking-Peptide - BP14678c from Abgent, a WuXi AppTec company
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UBE4A-Antibody-C-term-Blocking-Peptide - BP2110b from Abgent, a WuXi AppTec company
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UBE4A peptide - orb218247 from Biorbyt
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UBE4A Blocking Peptide - 33R-7789 from Fitzgerald
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UBE4A Blocking Peptide - abx063578 from Abbexa
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UBE4A fusion protein - Ag17120 from Proteintech Group
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UBE4A fusion protein - Ag16211 from Proteintech Group
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Recombinant Human UBE4A, His-tagged - UBE4A-3551H from Creative Biomart
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UBE4A Blocking Peptide - CBP2384 from Cohesion Biosciences
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UBE4A Peptide - BS5971P from Bioworld Technology
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Recombinant Human Ubiquitin conjugation factor E4 A(UBE4A) ,partial - CSB-YP619860HU CSB-EP619860HU CSB-BP619860HU CSB-MP619860HU from Cusabio
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Recombinant Protein E4(E4) - CSB-YP356815HNF CSB-EP356815HNF CSB-BP356815HNF CSB-MP356815HNF from Cusabio
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UBE4A - TP317407 from Acris Antibodies
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UBE4A Protein - NBP2-47590PEP from Novus Biologicals
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UBE4A-Antibody-N-term-Blocking-Peptide - BP2110a from Abgent, a WuXi AppTec company
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UBE4A Peptide, Human - M34GP16985H from Creative Peptides
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UBE4A Recombinant Protein Antigen - NBP2-56653PEP from Novus Biologicals
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Protein E4 (E4), Recombinant Protein - MBS1223040 from MyBioSource
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Recombinant Human UBE4A Protein, MYC/DDK-tagged - UBE4A-480H from Creative Biomart
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