COPE

Gene Symbol	COPE
Entrez Gene	11316
Alt Symbol	epsilon-COP
Species	Human
Gene Type	protein-coding
Description	coatomer protein complex, subunit epsilon
Other Description	coatomer epsilon subunit|coatomer subunit epsilon|epsilon coat protein|epsilon-coat protein
Swissprots	Q6IBB8 A6NKA3 A6NE29 Q9UGP6 O76097 O14579
Accessions	AAB81543 AAC24612 CBX84922 CBX84941 EAW84748 EAW84749 EAW84750 EAW84751 EAW84752 EAW84753 EAW84754 EAW84755 EAW84756 EAW84757 O14579 AF092438 AAP97213 AI680336 AJ131182 CAA10316 AJ249366 CAB55628 AK023303 AK222584 BAD96304 AK315281 BAG37690 AL136928 CAB66862 AM393761 CAL38636 BC003155 AAH03155 BC007250 AAH07250 BC017285 AAH17285 BC052619 BI520280 CR456886 CAG33167 DQ893417 ABM84343 DQ896735 ABM87734 XM_011527655 XP_011525957 XM_011527656 XP_011525958 NM_007263 NP_009194 NM_199442 NP_955474 NM_199444 NP_955476
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP- ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

COPE 293T Cell Transient Overexpression Lysate(Denatured) - H00011316-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

COPE overexpression lysate - LY404568 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COPE overexpression lysate - LY430836 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COPE 293 Cell Lysate - 407529 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

COPE Overexpression Lysate (Native) - NBL1-09378 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COPE Over-expression Lysate Product - GWB-31F6A6 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

COPE Overexpression Lysate (Denatured) - H00011316-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human COPE Knockdown Stable Cell Line - CSC-DC003496 from Creative biogene Category Cell Line Species Human

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