COPE

Gene Symbol	COPE
Entrez Gene	11316
Alt Symbol	epsilon-COP
Species	Human
Gene Type	protein-coding
Description	coatomer protein complex, subunit epsilon
Other Description	coatomer epsilon subunit|coatomer subunit epsilon|epsilon coat protein|epsilon-coat protein
Swissprots	Q6IBB8 A6NKA3 A6NE29 Q9UGP6 O76097 O14579
Accessions	AAB81543 AAC24612 CBX84922 CBX84941 EAW84748 EAW84749 EAW84750 EAW84751 EAW84752 EAW84753 EAW84754 EAW84755 EAW84756 EAW84757 O14579 AF092438 AAP97213 AI680336 AJ131182 CAA10316 AJ249366 CAB55628 AK023303 AK222584 BAD96304 AK315281 BAG37690 AL136928 CAB66862 AM393761 CAL38636 BC003155 AAH03155 BC007250 AAH07250 BC017285 AAH17285 BC052619 BI520280 CR456886 CAG33167 DQ893417 ABM84343 DQ896735 ABM87734 XM_011527655 XP_011525957 XM_011527656 XP_011525958 NM_007263 NP_009194 NM_199442 NP_955474 NM_199444 NP_955476
Function	The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP- ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human COPE Gene cDNA Clone - orb142620 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

COPE - MBS1275571 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC003155

Human COPE cDNA clone(NM_199442.1) - CDFG013145 from Creative Biomart Species Human Accession NM_199442.1

Human COPE cDNA clone(NM_199444.1) - CDFG013147 from Creative Biomart Species Human Accession NM_199444.1

Human COPE cDNA clone(NM_007263.3) - CDFH004079 from Creative Biomart Species Human Accession NM_007263.3

Human COPE ORF Clone(NM_007263.3) - CDCL159442 from Creative Biomart Species Human Accession NM_007263.3

Human COPE ORF Clone(NM_007263.3) - CDCR294742 from Creative Biomart Species Human Accession NM_007263.3

Human COPE ORF Clone(NM_007263.3) - CDCR294743 from Creative Biomart Species Human Accession NM_007263.3

Human COPE ORF Clone(NM_007263.3) - CDCR294744 from Creative Biomart Species Human Accession NM_007263.3

Human COPE ORF Clone(NM_199442.1) - CDCR326844 from Creative Biomart Species Human Accession NM_199442.1

Human COPE ORF Clone(NM_199442.1) - CDCR326845 from Creative Biomart Species Human Accession NM_199442.1

Human COPE ORF Clone(NM_199444.1) - CDCR326848 from Creative Biomart Species Human Accession NM_199444.1

Human COPE ORF Clone(NM_199444.1) - CDCR326849 from Creative Biomart Species Human Accession NM_199444.1

Human epsilon-COP Gene ORF cDNA clone in cloning vector - HG14265-G from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14265-NF from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14265-NM from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14265-CF from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14265-CM from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, N-His tag - HG14265-NH from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14265-ANG from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14265-ACG from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, N-HA tag - HG14265-NY from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, C-His tag - HG14265-CH from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid - HG14265-UT from Sino Biological Species Human

Human epsilon-COP Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14265-ACR from Sino Biological Species Human

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