Gene Symbol | FTSJ2 |
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Entrez Gene | 29960 |
Alt Symbol | FJH1, HEL97, MRM2, RRMJ2 |
Species | Human |
Gene Type | protein-coding |
Description | FtsJ RNA methyltransferase homolog 2 (E. coli) |
Other Description | 16S rRNA (uridine(1369)-2'-O)-methyltransferase|16S rRNA [Um1369] 2'-O-methyltransferase|FtsJ homolog 2|MRM2 RNA methyltransferase homolog|cell division protein FtsJ|epididymis luminal protein 97|protein ftsJ homolog 2|putative ribosomal RNA methyltransferase 2|rRNA (uridine-2'-O-)-methyltransferase|rRNA methyltransferase 2, mitochondrial |
Swissprots | Q24JR8 Q9UI43 |
Accessions | EAW87223 EAW87224 Q9UI43 AF093415 AAF22488 AK024635 AK302060 BAG63450 BC017106 BC017181 BC114514 AAI14515 BC114564 AAI14565 CR749618 CAH18412 EU794658 ACJ13712 NM_013393 NP_037525 NM_177442 |
Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O- methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. {ECO:0000269|PubMed:25009282, ECO:0000269|PubMed:25074936}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}. |
Tissue Specificity | Widely expressed, with highest expression in muscle, placenta, and heart. {ECO:0000269|PubMed:11827451}. |
FTSJ2 CRISPR/Cas9 KO Plasmid (h) - sc-412058 from Santa Cruz Biotechnology
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FTSJ2 HDR Plasmid (h) - sc-412058-HDR from Santa Cruz Biotechnology
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FTSJ2 Double Nickase Plasmid (h) - sc-412058-NIC from Santa Cruz Biotechnology
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FTSJ2 Double Nickase Plasmid (h2) - sc-412058-NIC-2 from Santa Cruz Biotechnology
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FTSJ2 CRISPR Activation Plasmid (h) - sc-412058-ACT from Santa Cruz Biotechnology
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FTSJ2 CRISPR Activation Plasmid (h2) - sc-412058-ACT-2 from Santa Cruz Biotechnology
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FTSJ2 Lentiviral Activation Particles (h) - sc-412058-LAC from Santa Cruz Biotechnology
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FTSJ2 Lentiviral Activation Particles (h2) - sc-412058-LAC-2 from Santa Cruz Biotechnology
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FTSJ2 siRNA (h) - sc-89863 from Santa Cruz Biotechnology
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FTSJ2 shRNA Plasmid (h) - sc-89863-SH from Santa Cruz Biotechnology
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FTSJ2 shRNA (h) Lentiviral Particles - sc-89863-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN8984 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8984 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06475 from Sigma-Aldrich
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FTSJ2 siRNA (Human) - CRH9301 from Cohesion Biosciences
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FTSJ2 - MBS8218685 from MyBioSource
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shRNA set against Human FTSJ2 (NM_013393.1) - SHH297573 from Creative biogene
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shRNA set against Human FTSJ2(NM_013393.1) - SHH069725 from Creative biogene
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Human FTSJ2 siRNA - orb269803 from Biorbyt
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FTSJ2 shRNA Plasmid (Human) - CHH9301 from Cohesion Biosciences
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FTSJ2 miRNA 3'UTR clone - MiUTR1H-03871 from Creative biogene
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