| Gene Symbol |
FAR2
|
| Entrez Gene |
55711
|
| Alt Symbol |
MLSTD1, SDR10E2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fatty acyl CoA reductase 2
|
| Other Description |
fatty acyl-CoA reductase 2|male sterility domain-containing protein 1|short chain dehydrogenase/reductase family 10E, member 2
|
| Swissprots |
Q96K12 Q9NVW8 Q9H0D5 F8VV73
|
| Accessions |
EAW96586 EAW96587 Q96K12 AK001324 BAA91625 AK001927 BAA91983 AK027756 BAB55347 AK129857 AK314670 BAG37227 AL136843 CAB66777 BC018460 BC022267 AAH22267 CB217408 DA068892 DA848036 XM_011520747 XP_011519049 XM_011520748 XP_011519050 NM_001271783 NP_001258712 NM_001271784 NP_001258713 NM_018099 NP_060569
|
| Function |
Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18:1 and C18:2 but low activity can be observed with C10-C14 substrates. {ECO:0000269|PubMed:15220348}.
|
| Subcellular Location |
Peroxisome membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Peroxisome in cells expressing low levels of the protein. Peroxisome and endoplasmic reticulum in cells expressing high levels of the protein.
|
| Top Pathways |
Peroxisome
|