USH1C

Gene Symbol USH1C
Entrez Gene 10083
Alt Symbol AIE-75, DFNB18, DFNB18A, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, PDZ73, PDZD7C, ush1cpst
Species Human
Gene Type protein-coding
Description Usher syndrome 1C (autosomal recessive, severe)
Other Description antigen NY-CO-38/NY-CO-37|autoimmune enteropathy-related antigen AIE-75|harmonin|renal carcinoma antigen NY-REN-3|usher syndrome type-1C protein
Swissprots Q9UPC3 Q96B29 A8K423 Q9UM04 Q9Y6N9 Q7RTU8 Q9UM17
Accessions EAW68431 EAW68432 EAW68433 EAW68434 Q9Y6N9 AB006955 BAA81739 AB018687 BAA81740 AF039699 AAC18048 AF039700 AAC18049 AK024943 BAB15040 AK225614 AK290788 BAF83477 AK300936 BAG62565 AL711953 BC016057 AAH16057 BK000147 DAA00086 BX641129 JF432227 ADZ15444 XM_011519831 XP_011518133 XM_011519832 XP_011518134 XM_011519833 XP_011518135 XM_011519834 XP_011518136 XR_930841 XR_930842 NM_001297764 NP_001284693 NM_005709 NP_005700 NM_153676 NP_710142 NR_123738
Function Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin (By similarity). Detected at the tip of cochlear hair cell stereocilia. {ECO:0000250}.
Tissue Specificity Expressed in small intestine, colon, kidney, eye and weakly in pancreas. Expressed also in vestibule of the inner ear. {ECO:0000269|PubMed:12588794}.

Harmonin CRISPR/Cas9 KO Plasmid (h) - sc-411412 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin HDR Plasmid (h) - sc-411412-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin Double Nickase Plasmid (h) - sc-411412-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin Double Nickase Plasmid (h2) - sc-411412-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin CRISPR Activation Plasmid (h) - sc-411412-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin CRISPR Activation Plasmid (h2) - sc-411412-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin Lentiviral Activation Particles (h) - sc-411412-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin Lentiviral Activation Particles (h2) - sc-411412-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Harmonin siRNA (h) - sc-40648 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Harmonin shRNA Plasmid (h) - sc-40648-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Harmonin shRNA (h) Lentiviral Particles - sc-40648-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USH1C RNAi - H00010083-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

USH1C RNAi - H00010083-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU086411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22549 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22549 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03981 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03981

USH1C siRNA (Human) - CRH6793 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USH1C - MBS8231688 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human USH1C (NM_005709.3) - SHH441116 from Creative biogene

Category siRNA
Species Reactivities Human

Human USH1C siRNA - orb267295 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USH1C shRNA Plasmid (Human) - CHH6793 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

USH1C miRNA 3'UTR clone - MiUTR4H-TG09697 from Creative biogene

Species Reactivities Human
Search more