| Gene Symbol |
Grin3b
|
| Entrez Gene |
170483
|
| Alt Symbol |
GluN3B, NR3B
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, ionotropic, NMDA3B
|
| Other Description |
N-methyl-D-aspartate receptor subunit NR3B|NMDA receptor 4|NMDAR3B|glutamate [NMDA] receptor subunit 3B|glutamate receptor ionotropic, NMDA 3B|nr4
|
| Swissprots |
Q8VHV0 Q91ZU9
|
| Accessions |
EDL31619 Q91ZU9 AF373861 AAL40418 AF396649 AAL10018 AY062435 AAL38983 BC115747 AAI15748 BC152738 AAI52739 XM_006513287 XP_006513350 XM_006513288 XP_006513351 XM_006513289 XP_006513352 NM_130455 NP_569722
|
| Function |
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:14602821}; Multi-pass membrane protein {ECO:0000269|PubMed:14602821}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:14602821}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane.
|
| Tissue Specificity |
Expressed in the facial nucleus and the ambiguus nucleus of the brainstem, pons, medulla, spinal cord and cerebellum. {ECO:0000269|PubMed:11717388, ECO:0000269|PubMed:12008020, ECO:0000269|PubMed:14602821}.
|
| Top Pathways |
Glutamatergic synapse, Amphetamine addiction, Nicotine addiction, Cocaine addiction, Alcoholism
|