NDUFS1

Gene Symbol NDUFS1
Entrez Gene 4719
Alt Symbol CI-75Kd, CI-75k, PRO1304
Species Human
Gene Type protein-coding
Description NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Other Description NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial|complex I 75kDa subunit|complex I, mitochondrial respiratory chain, 75-kD subunit|mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit
Swissprots B4DPG1 B4DUC1 Q8N1C4 Q53TR8 B4DIN9 Q8TCC9 B4DJA0 P28331 E7ENF3
Accessions AAY15061 ADP91534 ADP91535 ADP91536 ADP91537 ADP91538 ADP91539 ADP91540 ADP91541 ADP91542 ADP91543 ADP91544 ADP91545 ADP91546 ADP91547 ADP91548 ADP91549 ADP91550 ADP91551 ADP91552 ADP91553 ADP91554 ADP91555 ADP91556 ADP91557 ADP91558 ADP91559 ADP91560 ADP91561 ADP91562 ADP91563 ADP91564 ADP91565 ADP91566 ADP91567 ADP91568 ADP91569 ADP91570 ADP91571 ADP91572 ADP91573 EAW70379 EAW70380 P28331 AA150435 AK098395 AK295705 BAG58551 AK295966 BAG58743 AK295987 BAG58762 AK298320 BAG60573 AK300585 BAG62283 AW074155 BC004133 BC012068 AAH12068 BC018900 BC022368 AAH22368 BC030833 AAH30833 BQ882763 CA419316 DC413278 X61100 CAA43412 NM_001199981 NP_001186910 NM_001199982 NP_001186911 NM_001199983 NP_001186912 NM_001199984 NP_001186913 NM_005006 NP_004997
Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. {ECO:0000250}.
Subcellular Location Mitochondrion inner membrane.
Top Pathways Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation

NDUFS1 (E-8) - sc-271510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NDUFS1 (E-8): sc-271510. Western blot analysis of NDUFS1 expression in Raji (A), HeLa (B) and SK-MEL-28 (C) whole cell lysates.

NDUFS1 (D-20) - sc-50131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NDUFS1 (D-20): sc-50131. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

NDUFS1 (G-6) - sc-271387 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NDUFS1 (G-6): sc-271387. Western blot analysis of NDUFS1 expression in Raji (A), SK-MEL-28 (B) and Hep G2 (C) whole cell lysates.

NDUFS1 (Y-18) - sc-50133 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NDUFS1 (Y-18): sc-50133. Western blot analysis of NDUFS1 expression in mouse heart tissue extract.

NDUFS1 (H-300) - sc-99232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NDUFS1 (H-300): sc-99232. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

NDUFS1 (E-20) - sc-50132 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NDUFS1 (E-20): sc-50132. Western blot analysis of NDUFS1 expression in mouse heart tissue extract.

NDUFS1 (C-16) - sc-50130 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Ndufs1 antibody - ab185733 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat testis tissue labelling Ndufs1 with ab185733 at 1/200. Magnification: 400x.

Anti-Ndufs1 antibody - ab22094 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-Ndufs1 antibody (ab22094) at 1/1000 dilutionLane 1 : Total protein extract from E. coli with ~50ng to 100ng of a negative control fusion protein with an irrelevant antigen at 20 ugLane 2 : Total protein extract from E. coli with ~50ng to 500ng of the antigen fusion protein at 20 ugSecondaryRabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution

Anti-Ndufs1 antibody - ab134808 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Heart tissue labelling Ndufs1 with ab134808 at 5 µg/ml.

Anti-Ndufs1 antibody - ab52690 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-Ndufs1 antibody (ab52690) at 1/1000 dilutionLane 1 : The negative control lane: ~20ug of a total protein extract from E coli ~50ng to 100 ng of a recombinant fusion protein of an irrelevant antigen.Lane 2 : Test lane: ~20ug of a total protein extract from E coli with ~50ng to 500ng of the antigen (recombinant fusion protein). SecondaryRabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution

Anti-Ndufs1 antibody - ab104246 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Ndufs1 antibody (ab104246) at 0.3 µg/ml + Human Heart lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-Ndufs1 antibody - ab96428 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Ndufs1 antibody (ab96428) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

Anti-Ndufs1 antibody - ab137195 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Ndufs1 antibody (ab137195) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-Ndufs1 antibody - ab89768 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Ndufs1 antibody (ab89768) at 1 µg/ml + human spleen tissue lysate at 50 µg

Anti-Ndufs1 antibody - ab102552 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Ndufs1 antibody [EPR11521(B)] - ab169540 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11521(B)
All lanes : Anti-Ndufs1 antibody [EPR11521(B)] (ab169540) at 1/10000 dilutionLane 1 : Raji cell lysateLane 2 : HepG2 cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Ndufs1 antibody [EPR11521(B)] (Alexa Fluor® 488) - ab198954 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11521(B)
ab198954 staining Ndufs1 in HepG2 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198954 at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Ndufs1 antibody [EPR11521(B)] (Alexa Fluor® 647) - ab198956 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11521(B)
ab198956 staining Ndufs1 in HepG2 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198956 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Ndufs1 antibody [EPR11522(B)] - ab157221 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11522(B)
ab157221 showing +ve staining in Human normal prostate.

Anti-Ndufs1 antibody - N-terminal - ab157581 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Ndufs1 antibody - N-terminal (ab157581) at 1 µg/ml + Rat thymus lysate at 10 µgSecondaryGoat anti-rabbit IgG HRP

Anti-NDUFS1 Antibody (aa611-660) - LS-C116644 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NDUFS1 antibody LS-C116644 Western blot of Fetal Liver lysate.

Anti-NDUFS1 Antibody (aa620-669) - LS-C291349 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-NDUFS1 Antibody (aa662-707) - LS-C313849 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NDUFS1 Antibody (aa432-664) - LS-C186330 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Colon ca using NDUFS1 antibody at 1:250 dilution.
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