Gene Symbol | NDUFS1 |
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Entrez Gene | 4719 |
Alt Symbol | CI-75Kd, CI-75k, PRO1304 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
Other Description | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial|complex I 75kDa subunit|complex I, mitochondrial respiratory chain, 75-kD subunit|mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit |
Swissprots | B4DPG1 B4DUC1 Q8N1C4 Q53TR8 B4DIN9 Q8TCC9 B4DJA0 P28331 E7ENF3 |
Accessions | AAY15061 ADP91534 ADP91535 ADP91536 ADP91537 ADP91538 ADP91539 ADP91540 ADP91541 ADP91542 ADP91543 ADP91544 ADP91545 ADP91546 ADP91547 ADP91548 ADP91549 ADP91550 ADP91551 ADP91552 ADP91553 ADP91554 ADP91555 ADP91556 ADP91557 ADP91558 ADP91559 ADP91560 ADP91561 ADP91562 ADP91563 ADP91564 ADP91565 ADP91566 ADP91567 ADP91568 ADP91569 ADP91570 ADP91571 ADP91572 ADP91573 EAW70379 EAW70380 P28331 AA150435 AK098395 AK295705 BAG58551 AK295966 BAG58743 AK295987 BAG58762 AK298320 BAG60573 AK300585 BAG62283 AW074155 BC004133 BC012068 AAH12068 BC018900 BC022368 AAH22368 BC030833 AAH30833 BQ882763 CA419316 DC413278 X61100 CAA43412 NM_001199981 NP_001186910 NM_001199982 NP_001186911 NM_001199983 NP_001186912 NM_001199984 NP_001186913 NM_005006 NP_004997 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
Human NDUFS1 ELISA Kit (Sandwich ELISA) - LS-F9385 from LifeSpan Bioscience
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Human NDUFS1 ELISA Kit - abx152465 from Abbexa
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NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1), Human, ELISA Kit - SEJ794Hu from ARP American Research Products
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NDUFS1 (Human) IP-WB Antibody Pair - H00004719-PW1 from Acris Antibodies
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NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) , ELISA Kit - MBS9316968 from MyBioSource
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ELISA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1) - SEJ794Hu from Uscn Life Science Inc.
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ELISA Kit for NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1) - SEJ794Hu from Cloud-clone
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NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1), Human, ELISA Kit - DL-NDUFS1-Hu from ARP American Research Products
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Human NDUFS1 ELISA Kit - abx573114 from Abbexa
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Human NDUFS1 ELISA Kit - E025795 from Biobool
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NDUFS1 ELISA Kit (Human) (OKCD01062) - OKCD01062 from Aviva Systems Biology
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anti-NDUFS1 Antibody - ARG65573 from Arigo Biolaboratories
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anti-NDUFS1 antibody - ARG65261 from Arigo Biolaboratories
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NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1), ELISA Kit - MBS455832 from MyBioSource
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