Gene Symbol | NDUFS1 |
---|---|
Entrez Gene | 4719 |
Alt Symbol | CI-75Kd, CI-75k, PRO1304 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
Other Description | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial|complex I 75kDa subunit|complex I, mitochondrial respiratory chain, 75-kD subunit|mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit |
Swissprots | B4DPG1 B4DUC1 Q8N1C4 Q53TR8 B4DIN9 Q8TCC9 B4DJA0 P28331 E7ENF3 |
Accessions | AAY15061 ADP91534 ADP91535 ADP91536 ADP91537 ADP91538 ADP91539 ADP91540 ADP91541 ADP91542 ADP91543 ADP91544 ADP91545 ADP91546 ADP91547 ADP91548 ADP91549 ADP91550 ADP91551 ADP91552 ADP91553 ADP91554 ADP91555 ADP91556 ADP91557 ADP91558 ADP91559 ADP91560 ADP91561 ADP91562 ADP91563 ADP91564 ADP91565 ADP91566 ADP91567 ADP91568 ADP91569 ADP91570 ADP91571 ADP91572 ADP91573 EAW70379 EAW70380 P28331 AA150435 AK098395 AK295705 BAG58551 AK295966 BAG58743 AK295987 BAG58762 AK298320 BAG60573 AK300585 BAG62283 AW074155 BC004133 BC012068 AAH12068 BC018900 BC022368 AAH22368 BC030833 AAH30833 BQ882763 CA419316 DC413278 X61100 CAA43412 NM_001199981 NP_001186910 NM_001199982 NP_001186911 NM_001199983 NP_001186912 NM_001199984 NP_001186913 NM_005006 NP_004997 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
Human Ndufs1 full length protein - ab152559 from Abcam
|
||||||||||
NDUFS1 Antibody Blocking Peptide - LS-E20575 from LifeSpan Bioscience
|
||||||||||
NDUFS1 Antibody Blocking Peptide - LS-E27420 from LifeSpan Bioscience
|
||||||||||
Recombinant Human Ndufs1 Protein - H00004719-P01 from Novus Biologicals
|
||||||||||
NDUFS1 blocking peptide - GTX88087-PEP from GeneTex
|
||||||||||
NDUFS1 Blocking Peptide - 33R-9227 from Fitzgerald
|
||||||||||
NDUFS1 Blocking Peptide - abx062985 from Abbexa
|
||||||||||
NDUFS1 Peptide - AC21-2244-P from Abcore
|
||||||||||
NDUFS1 - H00004719-P01-10 from Acris Antibodies
|
||||||||||
NDUFS1 - H00004719-P01-25 from Acris Antibodies
|
||||||||||
NDUFS1 Peptide - 42-624P from ProSci
|
||||||||||
NDUFS1 fusion protein - ag3135 from Proteintech Group
|
||||||||||
Recombinant Human NDUFS1 - NDUFS1-272H from Creative Biomart
|
||||||||||
Recombinant NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1) - RPJ794Hu01 from Uscn Life Science Inc.
|
||||||||||
NDUFS1 Blocking Peptide - CBP1791 from Cohesion Biosciences
|
||||||||||
NDUFS1 Peptide - BS5818P from Bioworld Technology
|
||||||||||
Recombinant NADH Dehydrogenase Ubiquinone Fe-S Protein 1 (NDUFS1) - RPJ794Hu01 from Cloud-clone
|
||||||||||
Recombinant Human NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial(N - CSB-YP015660HU CSB-EP015660HU CSB-BP015660HU CSB-MP015660HU from Cusabio
|
||||||||||
NDUFS1 - TP305506 from Acris Antibodies
|
||||||||||
NDUFS1, Peptide - MBS427363 from MyBioSource
|
||||||||||
NDUFS1-Antibody-Center-Blocking-peptide - BP5678c from Abgent, a WuXi AppTec company
|
||||||||||
NDUFS1 Peptide, Human - M34GP10263H from Creative Peptides
|
||||||||||
NDUFS1 Recombinant Protein (OPCD05611) - OPCD05611 from Aviva Systems Biology
|
||||||||||
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1), Recombinant Protein - MBS717568 from MyBioSource
|
||||||||||
Ndufs1 Recombinant Protein Antigen - NBP2-56504PEP from Novus Biologicals
|