NDUFS1

Gene Symbol NDUFS1
Entrez Gene 4719
Alt Symbol CI-75Kd, CI-75k, PRO1304
Species Human
Gene Type protein-coding
Description NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Other Description NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial|complex I 75kDa subunit|complex I, mitochondrial respiratory chain, 75-kD subunit|mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit
Swissprots B4DPG1 B4DUC1 Q8N1C4 Q53TR8 B4DIN9 Q8TCC9 B4DJA0 P28331 E7ENF3
Accessions AAY15061 ADP91534 ADP91535 ADP91536 ADP91537 ADP91538 ADP91539 ADP91540 ADP91541 ADP91542 ADP91543 ADP91544 ADP91545 ADP91546 ADP91547 ADP91548 ADP91549 ADP91550 ADP91551 ADP91552 ADP91553 ADP91554 ADP91555 ADP91556 ADP91557 ADP91558 ADP91559 ADP91560 ADP91561 ADP91562 ADP91563 ADP91564 ADP91565 ADP91566 ADP91567 ADP91568 ADP91569 ADP91570 ADP91571 ADP91572 ADP91573 EAW70379 EAW70380 P28331 AA150435 AK098395 AK295705 BAG58551 AK295966 BAG58743 AK295987 BAG58762 AK298320 BAG60573 AK300585 BAG62283 AW074155 BC004133 BC012068 AAH12068 BC018900 BC022368 AAH22368 BC030833 AAH30833 BQ882763 CA419316 DC413278 X61100 CAA43412 NM_001199981 NP_001186910 NM_001199982 NP_001186911 NM_001199983 NP_001186912 NM_001199984 NP_001186913 NM_005006 NP_004997
Function Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. {ECO:0000250}.
Subcellular Location Mitochondrion inner membrane.
Top Pathways Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation

NDUFS1 CRISPR/Cas9 KO Plasmid (h) - sc-416401 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 HDR Plasmid (h) - sc-416401-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 Double Nickase Plasmid (h) - sc-416401-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 Double Nickase Plasmid (h2) - sc-416401-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 CRISPR Activation Plasmid (h) - sc-416401-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 CRISPR Activation Plasmid (h2) - sc-416401-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 Lentiviral Activation Particles (h) - sc-416401-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 Lentiviral Activation Particles (h2) - sc-416401-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NDUFS1 siRNA (h) - sc-61164 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDUFS1 shRNA Plasmid (h) - sc-61164-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NDUFS1 shRNA (h) Lentiviral Particles - sc-61164-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ndufs1 RNAi - H00004719-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU054201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15166 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15166 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08190 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08190

NDUFS1 siRNA (Human) - CRH3133 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NDUFS1 (NM_005006.6) - SHH350840 from Creative biogene

Category siRNA
Species Reactivities Human

Human NDUFS1 siRNA - orb263635 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NDUFS1 shRNA Plasmid (Human) - CHH3133 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NDUFS1 miRNA 3'UTR clone - MiUTR3H-01428 from Creative biogene

Species Reactivities Human
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