MSX1
| Gene Symbol | MSX1 |
|---|---|
| Entrez Gene | 4487 |
| Alt Symbol | ECTD3, HOX7, HYD1, STHAG1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | msh homeobox 1 |
| Other Description | homeobox 7|homeobox protein Hox-7|homeobox protein MSX-1|msh homeo box 1|msh homeobox 1-like protein|msh homeobox homolog 1 |
| Swissprots | Q96NY4 A0SZU5 P28360 A8K3M1 |
| Accessions | AAA58665 AAL17870 ABK81117 ADR64840 ADR64841 ADR64842 ADR64843 ADR64844 ADR64845 ADR64846 ADR64847 ADR64848 ADR64849 ADR64850 ADR64851 ADR64852 ADR64853 ADR64854 ADR64855 ADR64856 ADR64857 ADR64858 ADR64859 ADR64860 ADR64861 ADR64862 ADR64863 ADR64864 ADR64865 ADR64866 ADR64867 ADR64868 ADR64869 ADR64870 ADR64871 ADR64872 ADR64873 ADR64874 ADR64875 ADR64876 ADR64877 ADR64878 ADR64879 ADR64880 ADR64881 ADR64882 ADR64883 ADR64884 ADR64885 ADR64886 ADR64887 ADR64888 ADR64889 ADR64890 ADR64891 ADR64892 ADR64893 ADR64894 ADR64895 ADR64896 ADR64897 ADR64898 ADR64899 ADR64900 ADR64901 ADR64902 ADR64903 ADR64904 ADR64905 ADR64906 ADR64907 ADR64908 ADR64909 ADR64910 ADR64911 ADR64912 ADR64913 ADR64914 ADR64915 ADR64916 ADR64917 ADR64918 ADR64919 ADR64920 ADR64921 ADR64922 ADR64923 ADR64924 ADR64925 ADR64926 ADR64927 ADR64928 ADR64929 ADR64930 ADR64931 ADR64932 ADR64933 EAW82420 P28360 AK290636 BAF83325 AU117561 BC021285 AAH21285 BC067353 AAH67353 BU624994 DB356637 M97676 AAA52683 NM_002448 NP_002439 |
| Function | Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity. {ECO:0000269|PubMed:11369996, ECO:0000269|PubMed:12807959}. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | Expressed in the developing nail bed mesenchyme. {ECO:0000269|PubMed:11369996}. |
| Top Pathways | HTLV-I infection |
Msx-1 CRISPR/Cas9 KO Plasmid (h) - sc-405732 from Santa Cruz Biotechnology
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Msx-1 HDR Plasmid (h) - sc-405732-HDR from Santa Cruz Biotechnology
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Msx-1 Double Nickase Plasmid (h) - sc-405732-NIC from Santa Cruz Biotechnology
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Msx-1 Double Nickase Plasmid (h2) - sc-405732-NIC-2 from Santa Cruz Biotechnology
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Msx-1 CRISPR Activation Plasmid (h) - sc-405732-ACT from Santa Cruz Biotechnology
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Msx-1 CRISPR Activation Plasmid (h2) - sc-405732-ACT-2 from Santa Cruz Biotechnology
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Msx-1 Lentiviral Activation Particles (h) - sc-405732-LAC from Santa Cruz Biotechnology
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Msx-1 Lentiviral Activation Particles (h2) - sc-405732-LAC-2 from Santa Cruz Biotechnology
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Msx-1 siRNA (h) - sc-43945 from Santa Cruz Biotechnology
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Msx-1 shRNA Plasmid (h) - sc-43945-SH from Santa Cruz Biotechnology
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Msx-1 shRNA (h) Lentiviral Particles - sc-43945-V from Santa Cruz Biotechnology
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MSX1 RNAi - H00004487-R01 from Novus Biologicals
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MISSION® esiRNA - EHU147951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14667 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14667 from Sigma-Aldrich
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MSX1 siRNA (Human) - CRH2979 from Cohesion Biosciences
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shRNA set against Human MSX1 (NM_002448.3) - SHH345908 from Creative biogene
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shRNA set against Human MSX1(NM_002448.3) - SHH204473 from Creative biogene
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Msx-1 CRISPR/Cas9 KO Plasmid (h2) - sc-405732-KO-2 from Santa Cruz Biotechnology
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Msx-1 HDR Plasmid (h2) - sc-405732-HDR-2 from Santa Cruz Biotechnology
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Human MSX1 siRNA - orb263481 from Biorbyt
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MSX1 shRNA Plasmid (Human) - CHH2979 from Cohesion Biosciences
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MSX1 miRNA 3'UTR clone - MiUTR1H-06487 from Creative biogene
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