| Gene Symbol | ATP6V1G2 |
|---|---|
| Entrez Gene | 534 |
| Alt Symbol | ATP6G, ATP6G2, NG38, VMA10 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| Other Description | ATPase, H+ transporting, lysosomal (vacuolar proton pump)|H(+)-transporting two-sector ATPase, subunit G2|V-ATPase 13 kDa subunit 2|V-type proton ATPase subunit G 2|vacuolar ATP synthase subunit G 2|vacuolar proton pump G subunit 2 |
| Swissprots | O95670 Q5HYU8 B5MEF0 Q5RJ63 Q2L6F8 |
| Accessions | BAB63399 BAC00863 BAC54952 BAD74057 BAD74058 BAE78636 BAF31286 CAA75073 EAX03414 EAX03416 O95670 AA401769 BC047791 BC068023 AAH68023 BC119726 AAI19727 BC119727 AAI19728 BP195978 C20601 NM_001204078 NP_001191007 NM_130463 NP_569730 NM_138282 NP_612139 |
| Function | Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Subcellular Location | Melanosome {ECO:0000269|PubMed:17081065}. Note=Highly enriched in late-stage melanosomes. |
| Tissue Specificity | Brain. {ECO:0000269|PubMed:12384298}. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |