| Gene Symbol |
ALG2
|
| Entrez Gene |
85365
|
| Alt Symbol |
CDGIi, CMSTA3, NET38, hALPG2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ALG2, alpha-1,3/1,6-mannosyltransferase
|
| Other Description |
GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase|GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase|GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase|alpha-1,3-mannosyltransferase ALG2|alpha-1,3/1,6-mannosyltransferase ALG2|asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)|asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)|asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog|asparagine-linked glycosylation protein 2 homolog|homolog of yeast ALG2
|
| Swissprots |
Q8NC39 A2A2Y0 Q9H553 Q8NBX2
|
| Accessions |
CAF86196 CAF86774 EAW58908 EAW58909 EAW58910 EAW58911 Q9H553 AA017454 AB161356 BAD11905 AK027417 BAB55099 AK027814 BAG51380 AK074704 BAC11150 AK074988 BAC11337 AK075172 BAC11449 AK075189 AY358697 AAQ89060 BC015126 BC017876 AAH17876 DA076693 DB019023 DQ891989 ABM82915 DQ895179 ABM86105 NM_033087 NP_149078 NR_024532 NM_197973
|
| Function |
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate. {ECO:0000269|PubMed:12684507}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
N-Glycan biosynthesis
|
![Western Blot: ALG2 Overexpression Lysate [H00085365-T01] - Lane 1: ALG2 transfected lysate (45.87 KDa) Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/29109_ALG2%2520Overexpression%2520Lysate-Western%2520Blot-H00085365-T01-img0002.jpg)