| Gene Symbol | COL4A5 |
|---|---|
| Entrez Gene | 1287 |
| Alt Symbol | ASLN, ATS, CA54 |
| Species | Human |
| Gene Type | protein-coding |
| Description | collagen, type IV, alpha 5 |
| Other Description | collagen IV, alpha-5 polypeptide|collagen alpha-5(IV) chain|collagen of basement membrane, alpha-5 chain|collagen type IV alpha 5|dA149D17.3|dA24A23.1 |
| Swissprots | Q9NUB7 Q16126 Q16006 Q6LD84 P29400 Q7Z700 |
| Accessions | AAA51558 AAB31853 AAB33374 AAC27816 AAF66217 CAA85512 EAX02683 EAX02684 EAX02685 EAX02686 P29400 AK294066 BAG57411 AK307900 AK311302 BC035387 AAH35387 BC151846 AAI51847 BU688037 BX641049 DA461056 KM282618 AIW39922 M31115 AAA52045 M58526 AAA99480 M90464 AAA52046 S59334 AAD13909 S69168 AAC60612 XM_005262070 XP_005262127 XM_005262072 XP_005262129 XM_006724616 XP_006724679 XM_011530849 XP_011529151 XM_011530850 XP_011529152 XM_011530851 XP_011529153 NM_000495 NP_000486 NM_033380 NP_203699 NM_033381 |
| Function | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. |
| Tissue Specificity | Isoform 2 is found in kidney. |
| Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Protein digestion and absorption |