PEAR1

Gene Symbol PEAR1
Entrez Gene 375033
Alt Symbol JEDI, MEGF12
Species Human
Gene Type protein-coding
Description platelet endothelial aggregation receptor 1
Other Description hPEAR1|multiple EGF-like domains protein 12|multiple EGF-like-domains 12|multiple epidermal growth factor-like domains protein 12
Swissprots Q8TEK2 Q5VY43
Accessions Q5VY43 AK074121 BAB84947 AK098809 BAC05419 BC172296 AAI72296 XM_005245141 XP_005245198 XM_006711302 XP_006711365 XM_011509508 XP_011507810 XM_011509509 XP_011507811 XM_011509510 XP_011507812 XM_011509511 XP_011507813 XM_011509512 XP_011507814 NM_001080471 NP_001073940 NM_207369
Function When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Detected on the cell surface in resting platelets. {ECO:0000269|PubMed:15851471}.
Tissue Specificity Expressed in umbilical vein endothelial cells and platelets (at protein level). Expressed in heart, kidney, skeletal muscle, pancreas, ovary, breast, lung, brain cortex, hypothalamus, spinal cord, dorsal root ganglion, endothelial cells of umbilical cord artery and vein, megakaryocytes, osteoblasts, coronary muscle and erythroid cells. Weakly expressed in peripheral blood leukocytes and macrophages.

PEAR1 (G-14) - sc-163219 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PEAR1 (H-110) - sc-292937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PEAR1 (H-110): sc-292937. Western blot analysis of PEAR1 expression in non-transfected 293T: sc-117752 (A), human PEAR1 transfected 293T: sc-372288 (B) and MDA-MB-231 (C) whole cell lysates.

Anti-PEAR1 antibody - ab122261 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122261, at 1/35, staining PEAR1 in paraffin embedded Human bone marrow tissue by Immunohistochemistry.

Anti-PEAR1 Antibody (aa961-990) - LS-C163511 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PEAR1 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PEAR1 Antibody (C-Terminus) - LS-C115929 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of PEAR1 in human kidney tissue with PEAR1 antibody at 20 ug/ml.

Anti-PEAR1 Antibody (aa21-754) - LS-C74227 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PEAR1 Antibody (aa21-754, clone 12K158, APC) - LS-C182927 from LifeSpan Bioscience

Prices $635.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 12K158

Anti-PEAR1 Antibody (aa21-754, clone 12K158, PE) - LS-C182928 from LifeSpan Bioscience

Prices $575.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 12K158

Anti-PEAR1 Antibody (aa961-990, AP) - LS-C238906 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa961-990, APC) - LS-C238908 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa961-990, Biotin) - LS-C238909 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa961-990, FITC) - LS-C238910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa961-990, Azide-free, HRP) - LS-C248447 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa961-990, PE) - LS-C238913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PEAR1 Antibody (aa968-998) - LS-C323927 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

PEAR1 Antibody - AF4527 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Human CD41+ platelets were stained with Human PEAR1 Antigen Affinity‑purified Polyclonal Antibody (Catalog # AF4527, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0108).

PEAR1 Antibody (492621) - MAB4527 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 492621
Human peripheral blood platelets were stained with Mouse Anti-Human PEAR1 Monoclonal Antibody (Catalog # MAB4527) followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0101B) and Integrin  alpha  2b/CD41 Fluorescein-conjugated Monoclonal Antibody. Quadrant markers were set based on isotype control antibody staining (Catalog # MAB002).

PEAR1 Antibody - NBP1-90449 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PEAR1 Antibody [NBP1-90449] - Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome.

PEAR1 Antibody [Biotin] - BAF4527 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

PEAR1 Antibody (492621) [Phycoerythrin] - FAB4527P from Novus Biologicals

Prices $299.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 492621
Human peripheral blood platelets were stained with anti-human Integrin a2b/CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human PEAR1 PE-conjugated Monoclonal Antibody (Catalog # FAB4527P) or (B) Mouse IgG2A Phycoerythrin Isotype Control (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.

PEAR1 Antibody (492621) [Alexa Fluor 488] - FAB4527G from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 492621
Human peripheral blood platelets were stained with Mouse Anti-Human Integrin a2b/CD41 APC-conjugated Monoclonal Antibody (Catalog # FAB7616A) and either (A) Mouse Anti-Human PEAR1 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB4527G) or (B) Mouse IgG2A Alexa Fluor 488 Isotype Control (Catalog # IC003G). View our protocol for Staining Membrane-associated Proteins.

PEAR1 Antibody (492621) [Allophycocyanin] - FAB4527A from Novus Biologicals

Prices $339.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 492621
Human peripheral blood platelets were stained with anti-human Integrin a2b/CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human PEAR1 APC-conjugated Monoclonal Antibody (Catalog # FAB4527A) or (B) Mouse IgG2A Allophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

Anti-PEAR1 antibody produced in rabbit - HPA035217 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PEAR1: <B>Cat. No. HPA035217</B>: Immunohistochemical staining of human bone marrow shows strong positivity in megakaryocytes and platelets.

Anti-PEAR1 antibody produced in rabbit - SAB3500588 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PEAR1: <B>Cat. No. SAB3500588</B>: PEAR1 in rat kidney tissue lysate with PEAR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

PEAR1 Antibody - C-terminal region (OAAB00341) - OAAB00341 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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