PEAR1

Gene Symbol PEAR1
Entrez Gene 375033
Alt Symbol JEDI, MEGF12
Species Human
Gene Type protein-coding
Description platelet endothelial aggregation receptor 1
Other Description hPEAR1|multiple EGF-like domains protein 12|multiple EGF-like-domains 12|multiple epidermal growth factor-like domains protein 12
Swissprots Q8TEK2 Q5VY43
Accessions Q5VY43 AK074121 BAB84947 AK098809 BAC05419 BC172296 AAI72296 XM_005245141 XP_005245198 XM_006711302 XP_006711365 XM_011509508 XP_011507810 XM_011509509 XP_011507811 XM_011509510 XP_011507812 XM_011509511 XP_011507813 XM_011509512 XP_011507814 NM_001080471 NP_001073940 NM_207369
Function When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Detected on the cell surface in resting platelets. {ECO:0000269|PubMed:15851471}.
Tissue Specificity Expressed in umbilical vein endothelial cells and platelets (at protein level). Expressed in heart, kidney, skeletal muscle, pancreas, ovary, breast, lung, brain cortex, hypothalamus, spinal cord, dorsal root ganglion, endothelial cells of umbilical cord artery and vein, megakaryocytes, osteoblasts, coronary muscle and erythroid cells. Weakly expressed in peripheral blood leukocytes and macrophages.

PEAR1 CRISPR/Cas9 KO Plasmid (h) - sc-407627 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 HDR Plasmid (h) - sc-407627-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 Double Nickase Plasmid (h) - sc-407627-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 Double Nickase Plasmid (h2) - sc-407627-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 CRISPR Activation Plasmid (h) - sc-407627-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 CRISPR Activation Plasmid (h2) - sc-407627-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 Lentiviral Activation Particles (h) - sc-407627-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 Lentiviral Activation Particles (h2) - sc-407627-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PEAR1 siRNA (h) - sc-88802 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PEAR1 shRNA Plasmid (h) - sc-88802-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PEAR1 shRNA (h) Lentiviral Particles - sc-88802-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU089741 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16604 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16604 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PEAR1 siRNA (Human) - CRJ7652 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PEAR1 (NM_001080471.1) - SHH373332 from Creative biogene

Category siRNA
Species Reactivities Human

Human PEAR1 siRNA - orb278153 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PEAR1 shRNA Plasmid (Human) - CHJ7652 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PEAR1 miRNA 3'UTR clone - MiUTR1H-07771 from Creative biogene

Species Reactivities Human
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