Gene Symbol |
Atp1b1
|
Entrez Gene |
11931
|
Alt Symbol |
Atp4b, Atpb, Atpb-1, NKbeta1
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ATPase, Na+/K+ transporting, beta 1 polypeptide
|
Other Description |
sodium/potassium ATPase beta subunit|sodium/potassium-dependent ATPase subunit beta-1|sodium/potassium-transporting ATPase subunit beta-1
|
Swissprots |
P14094
|
Accessions |
EDL39248 EDL39249 EDL39250 EDL39251 EDL39252 P14094 AK005071 BAB23795 AK010677 BAB27109 AK140862 BAE24500 AK160405 BAE35773 AK161891 BAE36624 AK162938 BAE37124 BC027319 AAH27319 BC094070 AAH94070 EF437334 ABS83510 X16646 CAA34639 X61433 CAA43675 NM_009721 NP_033851
|
Function |
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
|
Subcellular Location |
Cell membrane; Single-pass type II membrane protein.
|
Top Pathways |
Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis
|