| Gene Symbol |
DSC3
|
| Entrez Gene |
1825
|
| Alt Symbol |
CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
desmocollin 3
|
| Other Description |
cadherin family member 3|desmocollin-3|desmocollin-4
|
| Swissprots |
Q14200 A6NN35 Q9HAZ9 Q14574
|
| Accessions |
AAG23426 AAG23427 CAC81269 EAX01247 EAX01248 EAX01249 Q14574 AF297090 AAG17896 AI123917 AK001100 AK074475 AK291748 BAF84437 BG214334 BG697535 D17427 BAA04249 DA860471 X83929 CAA58781 NM_001941 NP_001932 NM_024423 NP_077741
|
| Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
|
| Tissue Specificity |
Epidermis, buccal mucosa, esophagus and cervix.
|