Gene Symbol | DSC3 |
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Entrez Gene | 1825 |
Alt Symbol | CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP |
Species | Human |
Gene Type | protein-coding |
Description | desmocollin 3 |
Other Description | cadherin family member 3|desmocollin-3|desmocollin-4 |
Swissprots | Q14200 A6NN35 Q9HAZ9 Q14574 |
Accessions | AAG23426 AAG23427 CAC81269 EAX01247 EAX01248 EAX01249 Q14574 AF297090 AAG17896 AI123917 AK001100 AK074475 AK291748 BAF84437 BG214334 BG697535 D17427 BAA04249 DA860471 X83929 CAA58781 NM_001941 NP_001932 NM_024423 NP_077741 |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. |
Tissue Specificity | Epidermis, buccal mucosa, esophagus and cervix. |
DSC3 CRISPR/Cas9 KO Plasmid (h) - sc-404696 from Santa Cruz Biotechnology
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DSC3 HDR Plasmid (h) - sc-404696-HDR from Santa Cruz Biotechnology
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DSC3 Double Nickase Plasmid (h) - sc-404696-NIC from Santa Cruz Biotechnology
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DSC3 Double Nickase Plasmid (h2) - sc-404696-NIC-2 from Santa Cruz Biotechnology
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DSC3 CRISPR Activation Plasmid (h) - sc-404696-ACT from Santa Cruz Biotechnology
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DSC3 CRISPR Activation Plasmid (h2) - sc-404696-ACT-2 from Santa Cruz Biotechnology
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DSC3 Lentiviral Activation Particles (h) - sc-404696-LAC from Santa Cruz Biotechnology
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DSC3 Lentiviral Activation Particles (h2) - sc-404696-LAC-2 from Santa Cruz Biotechnology
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DSC3 siRNA (h) - sc-43111 from Santa Cruz Biotechnology
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DSC3 shRNA Plasmid (h) - sc-43111-SH from Santa Cruz Biotechnology
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DSC3 shRNA (h) Lentiviral Particles - sc-43111-V from Santa Cruz Biotechnology
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Desmocollin-1 RNAi - H00001823-R02 from Novus Biologicals
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Desmocollin-2 RNAi - H00001824-R02 from Novus Biologicals
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MISSION® esiRNA - EHU085451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7497 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7497 from Sigma-Aldrich
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DSC3 siRNA (Human) - CRH1274 from Cohesion Biosciences
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Desmocollin-3 RNAi - H00001825-R02 from Novus Biologicals
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Desmocollin-3 RNAi - H00001825-R01 from Novus Biologicals
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DSC3 - MBS826917 from MyBioSource
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shRNA set against Human DSC3 (NM_001941.3) - SHH281141 from Creative biogene
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shRNA set against Human DSC3(NM_024423.2) - SHH016139 from Creative biogene
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shRNA set against Human DSC3(NM_001941.3) - SHH016157 from Creative biogene
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Human DSC3 siRNA - orb261776 from Biorbyt
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DSC3 shRNA Plasmid (Human) - CHH1274 from Cohesion Biosciences
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