ANXA1

Gene Symbol ANXA1
Entrez Gene 327662
Alt Symbol p35
Species Bovine
Gene Type protein-coding
Description annexin A1
Other Description annexin I|annexin-1|calpactin II|calpactin-2|chromobindin-9|lipocortin I|phospholipase A2 inhibitory protein
Swissprots Q3ZBF5 Q58DU6 P46193
Accessions AAB25084 DAA26880 P46193 BC103375 AAI03376 BT021501 AAX46348 JQ796275 AFN52410 X56649 CAA39971 NM_175784 NP_786978
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. Binds muscle actin.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}. Basolateral cell membrane {ECO:0000250}. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages. {ECO:0000250}.

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