| Gene Symbol | HLA-C |
|---|---|
| Entrez Gene | 3107 |
| Alt Symbol | D6S204, HLA-JY3, HLC-C, PSORS1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | major histocompatibility complex, class I, C |
| Other Description | HLA class I histocompatibility antigen, C alpha chain|HLA class I histocompatibility antigen, Cw-1 alpha chain|MHC class I antigen heavy chain HLA-C|human leukocyte antigen-C alpha chain|major histocompatibility antigen HLA-C |
| Swissprots | Q29867 Q29652 O78083 Q29990 O78061 Q29631 Q9TQP9 Q9MY31 P10321 Q95463 Q95603 Q29865 O78203 P79498 P30508 O02863 O19652 O62882 O78062 O78166 O78211 O78214 P30509 Q29768 Q31627 Q860R1 Q860R2 Q99528 Q9GIK4 Q9TPS4 Q9UM32 Q9UM33 P30510 O62879 O78178 Q29641 Q30192 Q9MY35 Q9TQJ5 P30505 P30506 P30507 P30501 P30502 Q95604 O02864 O02958 Q29643 Q9MY30 Q29963 O19505 O78063 Q29989 P30504 O78067 O78072 O78090 O78149 Q29921 Q9UM42 Q29960 O78091 O78202 Q29862 Q29959 Q9MY74 Q9MYI3 Q9TNZ8 P30499 O02865 O19676 P30500 Q29986 Q9UQS9 P04222 O62883 O78060 O78068 O78069 P30503 Q29743 Q29992 Q29993 Q9GIK8 Q9TQB4 Q07000 O78165 Q29864 Q29991 Q31605 Q9BD28 Q9GJ33 Q9MY49 Q9TNN7 O02866 O62888 Q9TPV8 Q9TPX2 |
| Accessions | AAA59648 AAA59659 AAA59670 AAA59671 AAA59700 AAA59702 AAA81370 AAA81371 AAB02773 AAB03578 AAB03579 AAB03581 AAB03582 AAB03583 AAB03584 AAB03587 AAB03623 AAB03624 AAB04639 AAB48495 AAB48496 AAB48497 AAB62539 AAB66708 AAB66710 AAB66711 AAB70288 AAB70289 AAB70290 AAB70291 AAB70292 AAB70296 AAB80724 AAC14579 AAC14581 AAC17713 AAC17721 AAC27626 AAD37816 AAF29567 AAG10048 AAG53741 AAG53742 AAL49978 AAL87225 AAM44831 AAO84019 AAP30863 AAP84346 AAQ81571 AAR99590 AAR99591 AAR99594 AAS45436 AAS98883 AAT39426 AAT39989 AAT41622 AAU14145 AAV39503 AAX18631 AAX18632 AAX94769 AAX94770 AAX98239 ABC47332 ABC47333 ABC59292 ABD60574 ABD95971 ABF60562 ABG43099 ABG43100 ABG79048 ABG81776 ABG81862 ABG91051 ABH03035 ABQ23497 ACN81061 ACS12751 BAA11022 BAA13946 BAA22206 BAA22919 BAA84115 BAB63310 BAC54942 BAD77815 BAD77816 BAD77817 BAE76021 BAE76022 BAE78631 BAE78656 BAE87034 BAE93431 BAE93432 BAF96505 CAA05125 CAA25190 CAA75000 CAA75755 CAA75756 CAA76197 CAA76198 CAA76206 CAA76613 CAA76614 CAA80437 CAA96520 CAA99487 CAB02077 CAB02409 CAB37942 CAB37944 CAB37945 CAB38942 CAB40352 CAB41889 CAB44356 CAB44777 CAB45917 CAB45918 CAB46485 CAB53538 CAB53539 CAB65545 CAB65546 CAB65547 CAB65548 CAB71315 CAB71932 CAB71934 CAB71935 CAB71936 CAB71938 CAB71939 CAB71940 CAB86064 CAB95011 CAB97130 CAC01936 CAC04321 CAC04322 CAC05372 CAC11132 CAC12745 CAC18746 CAC19018 CAC19191 CAC24483 CAC36100 CAC79613 CAD12427 CAD12428 CAD12430 CAD12432 CAD12433 CAD12436 CAD12437 CAD12801 CAD27616 CAD29450 CAD29451 CAD44569 CAD44641 CAD45440 CAD45557 CAD47827 CAD47856 CAD56468 CAD59685 CAD70710 CAD70711 CAD79471 CAD79472 CAD90006 CAD90007 CAD90008 CAD90009 CAD90010 CAD90012 CAD98751 CAE22463 CAE22464 CAE22465 CAE30287 CAE30455 CAE30456 CAE30459 CAE30460 CAE84097 CAE84099 CAE84101 CAE84103 CAE84105 CAE84107 CAE85468 CAE85469 CAE92337 CAE92338 CAF05030 CAF18233 CAF32225 CAF32226 CAF32227 CAF32228 CAF32229 CAF33342 CAF33343 CAG25672 CAG25674 CAG26752 CAG26753 CAG26974 CAH17687 CAH40829 CAH65478 CAH65479 CAH65480 CAI29271 CAI40345 CAI48027 CAI53896 CAI64220 CAI94871 CAJ01384 CAJ31318 CAJ32664 CAJ32665 CAJ42902 CAJ43601 CAJ55680 CAJ55681 CAJ55682 CAJ55687 CAJ55690 CAJ55741 CAJ56101 CAJ84823 CAJ97443 CAK02799 CAK96162 CAL91416 CAM23872 EAX03374 EAX03375 EAX03376 EAX03377 EAX03378 EAX03379 EAX03380 EAX03381 EAX03382 P04222 P10321 P30499 P30501 P30504 P30505 P30508 P30510 Q29960 Q29963 Q95604 AF168611 AAD50823 AF196489 AAM76870 AF405691 AAL03994 AJ005199 CAA06438 AJ010748 CAA09340 AJ010749 CAA09341 AJ440716 CAD29433 AJ537578 CAD61205 AK024836 AK130592 AK301283 BAG62842 AK304527 BAG65328 AM237285 CAJ86551 AY732487 AAV33126 BC002463 AAH02463 BC004489 BC007814 AAH07814 BC008457 AAH08457 BC010542 AAH10542 BC033293 AAH33293 BC041078 CA395932 D38526 BAA07531 D49552 BAA08500 D49819 BAA08625 D50852 BAA32611 D50853 BAA32610 D50854 BAA32612 D64145 BAA19531 D64146 BAA19532 D64147 BAA19533 D64148 BAA19534 D64150 BAA19535 D64151 BAA19536 D64152 BAA19537 D83029 BAA11747 D83030 BAA32613 D83741 BAA32615 DQ891896 ABM82822 DQ895082 ABM86008 L38251 AAF26750 L77114 AAL40067 M11886 AAA52665 M12679 AAA59699 M21963 AAA59847 M24031 AAA00027 M24096 AAA59654 M24097 AAA59656 M26429 AAA59701 M26430 AAA59703 M26431 AAA59704 M26712 AAA52666 M28160 AAA36235 M28206 AAA57258 M28207 AAA53259 M84171 AAA59685 M84172 AAA59686 M84173 AAA59687 M84174 AAA59688 M84386 AAA59705 M99389 AAA88088 M99390 AAA88089 S74115 AAD14147 U06695 AAA92995 U06696 AAA92996 U07230 AAA17037 U09853 AAA50217 U41386 AAC32743 U41420 AAC32742 U57028 AAD11469 U62824 AAB67322 U91179 AAC51396 X58536 CAA41427 X70856 CAA50209 X70857 CAA50210 X76189 CAA53783 X82122 CAA57634 X83394 CAA58313 X97321 CAA65986 X98742 CAA67294 X99704 CAA68035 Y10520 CAA71531 Y11843 CAA72592 Z15144 CAA78850 Z33459 CAA83881 Z46809 CAA86839 Z46810 CAA86840 Z83247 CAB05845 NM_001243042 NP_001229971 NM_002117 NP_002108 |
| Function | Involved in the presentation of foreign antigens to the immune system. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Natural killer cell mediated cytotoxicity, Epstein-Barr virus infection, Cell adhesion molecules (CAMs), Viral carcinogenesis, Herpes simplex infection |