Gad2

Gene Symbol Gad2
Entrez Gene 14417
Alt Symbol 6330404F12Rik, GAD(65), GAD65, Gad-2
Species Mouse
Gene Type protein-coding
Description glutamic acid decarboxylase 2
Other Description 65 kDa glutamic acid decarboxylase|GAD-65|glutamate decarboxylase 2|glutamate decarboxylase 65 kDa isoform
Swissprots O35519 P48320
Accessions BAB20415 EDL08136 P48320 AF326549 AAL37395 AF326550 AAL37396 AK018118 AK136834 AK141473 BAE24695 AK161857 BC018380 AAH18380 BQ571205 D42051 BAA22893 KC134211 AFX68721 L16980 AAA93049 S67454 AAP14009 XM_011239023 XP_011237325 NM_008078 NP_032104
Function Catalyzes the production of GABA.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}.
Top Pathways Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism