Gene Symbol | Sost |
---|---|
Entrez Gene | 80722 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | sclerostin |
Other Description | sclerosteosis |
Swissprots | Q99P67 |
Accessions | EDM06161 Q99P67 AF326741 AAK13456 NM_030584 NP_085073 |
Function | Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000305}. |
Top Pathways | Wnt signaling pathway |