Gene Symbol | VIM |
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Entrez Gene | 7431 |
Alt Symbol | CTRCT30, HEL113 |
Species | Human |
Gene Type | protein-coding |
Description | vimentin |
Other Description | epididymis luminal protein 113 |
Swissprots | Q15869 Q6LER9 B0YJC2 P08670 Q96ML2 Q8N850 Q9NTM3 D3DRU4 Q548L2 Q15868 Q15867 |
Accessions | AAA61279 AAA61280 AAA61281 ACA06100 ACA06101 ACA06102 ACA06103 CAA36187 EAW86215 EAW86216 P08670 AF328728 AAN09720 AK056766 BAB71275 AK091813 BAG52420 AK093924 AK097336 BAC05002 AK098444 AK222482 BAD96202 AK222507 BAD96227 AK222602 BAD96322 AK290643 BAF83332 BC000163 AAH00163 BC030573 AAH30573 BC031031 BC066956 AAH66956 BQ050765 CR407690 CAG28618 EU794672 ACJ13726 M25246 AAA61282 X16478 CAA34499 X56134 CAA39600 Z19554 CAA79613 XM_006717500 XP_006717563 XM_011519649 XP_011517951 NM_003380 NP_003371 |
Function | Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. {ECO:0000269|PubMed:21746880}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21465480}. |
Tissue Specificity | Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines. {ECO:0000269|PubMed:2472876, ECO:0000269|PubMed:3371665}. |
Top Pathways | Epstein-Barr virus infection, MicroRNAs in cancer |
Vimentin CRISPR/Cas9 KO Plasmid (h) - sc-400035 from Santa Cruz Biotechnology
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Vimentin HDR Plasmid (h) - sc-400035-HDR from Santa Cruz Biotechnology
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Vimentin Double Nickase Plasmid (h) - sc-400035-NIC from Santa Cruz Biotechnology
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Vimentin Double Nickase Plasmid (h2) - sc-400035-NIC-2 from Santa Cruz Biotechnology
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Vimentin CRISPR Activation Plasmid (h) - sc-400035-ACT from Santa Cruz Biotechnology
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Vimentin CRISPR Activation Plasmid (h2) - sc-400035-ACT-2 from Santa Cruz Biotechnology
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Vimentin Lentiviral Activation Particles (h) - sc-400035-LAC from Santa Cruz Biotechnology
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Vimentin Lentiviral Activation Particles (h2) - sc-400035-LAC-2 from Santa Cruz Biotechnology
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Vimentin siRNA (h) - sc-29522 from Santa Cruz Biotechnology
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Vimentin shRNA Plasmid (h) - sc-29522-SH from Santa Cruz Biotechnology
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Vimentin shRNA (h) Lentiviral Particles - sc-29522-V from Santa Cruz Biotechnology
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Vimentin RNAi - H00007431-R01 from Novus Biologicals
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MISSION® esiRNA - EHU151861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22683 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22683 from Sigma-Aldrich
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VIM siRNA (Human) - CRH5085 from Cohesion Biosciences
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VIM - MBS8233895 from MyBioSource
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Vimentin - MBS826820 from MyBioSource
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shRNA set against Human VIM (NM_003380.3) - SHH442756 from Creative biogene
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Vimentin siRNA gene - orb219190 from Biorbyt
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VIM shRNA Plasmid (Human) - CHH5085 from Cohesion Biosciences
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VIM miRNA 3'UTR clone - MiUTR3H-02411 from Creative biogene
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