INPP5K

Gene Symbol	INPP5K
Entrez Gene	51763
Alt Symbol	PPS, SKIP
Species	Human
Gene Type	protein-coding
Description	inositol polyphosphate-5-phosphatase K
Other Description	inositol polyphosphate 5-phosphatase K|skeletal muscle and kidney-enriched inositol phosphatase
Swissprots	Q9P2R5 Q9NPJ5 B2R750 Q15733 D3DTH8 Q9BT40 B2R6I2
Accessions	BAA92342 EAW90614 EAW90615 EAW90616 EAW90617 EAW90618 Q9BT40 AB036829 BAA92340 AB036830 BAA92341 AK297955 BAH12695 AK303907 BAH14079 AK307293 AK312585 BAG35479 AK312844 BAG35697 BC004362 AAH04362 BG722885 BM510617 DQ892815 ABM83741 DQ896061 ABM87060 U45973 AAB03214 XM_005256683 XP_005256740 XM_005256685 XP_005256742 XM_005256686 XP_005256743 XM_011523934 XP_011522236 XM_011523935 XP_011522237 XM_011523936 XP_011522238 NM_001135642 NP_001129114 NM_016532 NP_057616 NM_130766 NP_570122
Function	Inositol 5-phosphatase which acts on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5- trisphosphate. May negatively regulate assembly of the actin cytoskeleton. {ECO:0000269|PubMed:10753883}.
Subcellular Location	Endoplasmic reticulum {ECO:0000269|PubMed:12536145}. Note=Following stimulation with EGF, translocates to membrane ruffles.
Tissue Specificity	Ubiquitously expressed with highest levels in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:10753883}.
Top Pathways	Insulin signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SKIP full length protein - ab132744 from Abcam Category Protein Source Wheat germ Species Human

INPP5K / SKIP Antibody Blocking Peptide - LS-E22359 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

INPP5K / SKIP Antibody Blocking Peptide - LS-E22360 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SKIP Recombinant Protein - H00051763-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human SKIP Protein - H00051763-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SKIP Protein - H00051763-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

INPP5K-Antibody-Center-Blocking-Peptide - BP8767c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

INPP5K Blocking Peptide - 33R-7285 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

INPP5K - H00051763-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

INPP5K - H00051763-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

INPP5K - H00051763-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

INPP5K - H00051763-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

INPP5K - H00051763-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

INPP5K - H00051763-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

INPP5K - H00051763-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

INPP5K fusion protein - ag7192 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

INPP5K fusion protein - Ag7744 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human INPP5K, His-tagged - INPP5K-31407TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Inositol polyphosphate 5-phosphatase K(INPP5K) - CSB-YP866277HU CSB-EP866277HU CSB-BP866277HU CSB-MP866277HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

INPP5K Protein - abx163939 from Abbexa Category Protein Species Human

INPP5K (transcript variant 1) - TP300092 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

INPP5K (transcript variant 2) - TP312090 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

INPP5K (transcript variant 3) - TP327852 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SKIP Recombinant Protein Antigen - NBP1-87034PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

INPP5K Peptide, Human - M34GP07668H from Creative Peptides Category Peptide Source Synthetic. Species Human

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