| Gene Symbol | TFB4 |
|---|---|
| Entrez Gene | 856169 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | TFIIH/NER complex subunit TFB4 |
| Other Description | - |
| Swissprots | Q12004 D6W462 |
| Accessions | DAA11478 Q12004 NM_001184153 NP_015381 |
| Function | Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro. {ECO:0000269|PubMed:10506223, ECO:0000269|PubMed:7961739, ECO:0000269|PubMed:8631896}. |
| Subcellular Location | Nucleus {ECO:0000250}. |
| Top Pathways | Nucleotide excision repair, Basal transcription factors |