Gene Symbol | HIST1H2AG |
---|---|
Entrez Gene | 8969 |
Alt Symbol | H2A.1b, H2A/p, H2AFP, H2AG, pH2A/f |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2ag |
Other Description | H2A histone family, member P|H2A.1|histone 1, H2ag|histone H2A type 1|histone H2A/p |
Swissprots | P0C0S8 Q76PA6 Q2M1R2 |
Accessions | AAN59968 EAX03083 AK312124 BAG35060 BC016677 AAH16677 BC067782 DQ891024 ABM81950 DQ894204 ABM85130 DQ894286 ABM85212 L19778 AAC24466 NM_021064 NP_066408 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |