Gene Symbol | BEST2 |
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Entrez Gene | 54831 |
Alt Symbol | VMD2L1 |
Species | Human |
Gene Type | protein-coding |
Description | bestrophin 2 |
Other Description | VMD2-like gene 1|bestrophin-2|vitelliform macular dystrophy 2-like 1|vitelliform macular dystrophy 2-like protein 1 |
Swissprots | Q8NFU1 Q53YQ8 Q9NXP0 |
Accessions | EAW84304 Q8NFU1 AF440756 AAM76995 AK000139 BAA90970 AK225232 AY515705 AAR99655 BC169236 BC169237 BC169238 XM_005259963 XP_005260020 NM_017682 NP_060152 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269|PubMed:11904445, ECO:0000269|PubMed:12907679, ECO:0000269|PubMed:18400985}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Mainly confined to the retinal pigment epithelium and colon. {ECO:0000269|PubMed:12032738}. |
Top Pathways | Salivary secretion |
Bestrophin-2 (D-12) - sc-74338 from Santa Cruz Biotechnology
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Bestrophin-2 (H-188) - sc-98568 from Santa Cruz Biotechnology
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Bestrophin-2 (K-15) - sc-74339 from Santa Cruz Biotechnology
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Anti-Bestrophin 2 antibody - ab32830 from Abcam
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Anti-BEST2 / Bestrophin-2 Antibody (Internal) IHC-plus⢠- LS-A8719 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, APC) - LS-C233129 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, Biotin) - LS-C233130 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, FITC) - LS-C233132 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, PE) - LS-C233133 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, Azide-free, HRP) - LS-C249519 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411) - LS-C329258 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa374-403) - LS-C156800 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (Internal) IHC-plus⢠- LS-A8721 from LifeSpan Bioscience
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Anti-BEST2 / Bestrophin-2 Antibody (aa381-411, AP) - LS-C233131 from LifeSpan Bioscience
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Bestrophin 2 Antibody - NB110-55620 from Novus Biologicals
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Bestrophin 2 Antibody - NBP1-91699 from Novus Biologicals
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Bestrophin 2 Polyclonal Antibody - bs-11041R from Bioss
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Bestrophin 2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11041R-A350 from Bioss
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Bestrophin 2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11041R-A488 from Bioss
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Bestrophin 2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11041R-A555 from Bioss
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Bestrophin 2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11041R-A647 from Bioss
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Bestrophin 2 Polyclonal Antibody, Cy3 Conjugated - bs-11041R-Cy3 from Bioss
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Bestrophin 2 Polyclonal Antibody, Cy5 Conjugated - bs-11041R-Cy5 from Bioss
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Bestrophin 2 Polyclonal Antibody, Cy5.5 Conjugated - bs-11041R-Cy5.5 from Bioss
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Bestrophin 2 Polyclonal Antibody, Cy7 Conjugated - bs-11041R-Cy7 from Bioss
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