| Gene Symbol |
BEST2
|
| Entrez Gene |
54831
|
| Alt Symbol |
VMD2L1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bestrophin 2
|
| Other Description |
VMD2-like gene 1|bestrophin-2|vitelliform macular dystrophy 2-like 1|vitelliform macular dystrophy 2-like protein 1
|
| Swissprots |
Q8NFU1 Q53YQ8 Q9NXP0
|
| Accessions |
EAW84304 Q8NFU1 AF440756 AAM76995 AK000139 BAA90970 AK225232 AY515705 AAR99655 BC169236 BC169237 BC169238 XM_005259963 XP_005260020 NM_017682 NP_060152
|
| Function |
Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269|PubMed:11904445, ECO:0000269|PubMed:12907679, ECO:0000269|PubMed:18400985}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Mainly confined to the retinal pigment epithelium and colon. {ECO:0000269|PubMed:12032738}.
|
| Top Pathways |
Salivary secretion
|