Gene Symbol | BEST2 |
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Entrez Gene | 54831 |
Alt Symbol | VMD2L1 |
Species | Human |
Gene Type | protein-coding |
Description | bestrophin 2 |
Other Description | VMD2-like gene 1|bestrophin-2|vitelliform macular dystrophy 2-like 1|vitelliform macular dystrophy 2-like protein 1 |
Swissprots | Q8NFU1 Q53YQ8 Q9NXP0 |
Accessions | EAW84304 Q8NFU1 AF440756 AAM76995 AK000139 BAA90970 AK225232 AY515705 AAR99655 BC169236 BC169237 BC169238 XM_005259963 XP_005260020 NM_017682 NP_060152 |
Function | Forms calcium-sensitive chloride channels. Permeable to bicarbonate. {ECO:0000269|PubMed:11904445, ECO:0000269|PubMed:12907679, ECO:0000269|PubMed:18400985}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Mainly confined to the retinal pigment epithelium and colon. {ECO:0000269|PubMed:12032738}. |
Top Pathways | Salivary secretion |
BEST2 / Bestrophin-2 Antibody Blocking Peptide - LS-E29457 from LifeSpan Bioscience
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BEST2 / Bestrophin-2 Antibody Blocking Peptide - LS-E29459 from LifeSpan Bioscience
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BEST2 / Bestrophin-2 Antibody Blocking Peptide - LS-E10023 from LifeSpan Bioscience
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BEST2-Antibody-C-term-Blocking-Peptide - BP9246b from Abgent, a WuXi AppTec company
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Bestrophin-2 control peptide - AP09913CP-N from Acris Antibodies
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Bestrophin 2 Recombinant Protein Antigen - NBP1-91699PEP from Novus Biologicals
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BEST2 Peptide, Human - M34GP01412H from Creative Peptides
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Recombinant Bestrophin 2 (BEST2) - RPU54716 from Biomatik
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Bestrophin 2 (BEST2), Recombinant Protein - MBS2086893 from MyBioSource
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Bestrophin-2 (BEST2), Recombinant Protein - MBS7010375 from MyBioSource
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