Gene Symbol | ABCA8 |
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Entrez Gene | 10351 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family A (ABC1), member 8 |
Other Description | ATP-binding cassette sub-family A member 8 |
Swissprots | C9JQE6 O94911 Q86WW0 A1L3U3 |
Accessions | EAW89068 EAW89069 O94911 AA448212 AB020629 BAA74845 AK090894 AK295876 BAG58673 AK304286 BAG65144 AK304360 BAG65201 AW590229 BC010392 BC024003 AAH24003 BC037309 AAH37309 BC047765 AAH47765 BC094689 AAH94689 BC130280 AAI30281 BC143971 BC143972 BG210966 BM665457 BM707283 CK824290 XM_005256938 XP_005256995 XM_005256940 XP_005256997 XM_011524188 XP_011522490 XM_011524189 XP_011522491 XM_011524190 XP_011522492 XM_011524191 XP_011522493 XM_011524192 XP_011522494 NM_001288985 NP_001275914 NM_001288986 NP_001275915 NM_007168 NP_009099 |
Function | ATP-dependent lipophilic drug transporter. {ECO:0000269|PubMed:12379217}. |
Subcellular Location | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed with higher expression in heart, skeletal muscle and liver. {ECO:0000269|PubMed:12379217}. |
Top Pathways | ABC transporters |
ABCA8 CRISPR/Cas9 KO Plasmid (h) - sc-409779 from Santa Cruz Biotechnology
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ABCA8 HDR Plasmid (h) - sc-409779-HDR from Santa Cruz Biotechnology
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ABCA8 Double Nickase Plasmid (h) - sc-409779-NIC from Santa Cruz Biotechnology
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ABCA8 Double Nickase Plasmid (h2) - sc-409779-NIC-2 from Santa Cruz Biotechnology
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ABCA8 CRISPR Activation Plasmid (h) - sc-409779-ACT from Santa Cruz Biotechnology
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ABCA8 CRISPR Activation Plasmid (h2) - sc-409779-ACT-2 from Santa Cruz Biotechnology
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ABCA8 Lentiviral Activation Particles (h) - sc-409779-LAC from Santa Cruz Biotechnology
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ABCA8 Lentiviral Activation Particles (h2) - sc-409779-LAC-2 from Santa Cruz Biotechnology
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ABCA8 siRNA (h) - sc-93930 from Santa Cruz Biotechnology
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ABCA8 shRNA Plasmid (h) - sc-93930-SH from Santa Cruz Biotechnology
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ABCA8 shRNA (h) Lentiviral Particles - sc-93930-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2625 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06630 from Sigma-Aldrich
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ABCA8 siRNA (Human) - CRH7017 from Cohesion Biosciences
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ABCA8 RNAi - H00010351-R01 from Novus Biologicals
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ABCA8 - MBS8233962 from MyBioSource
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shRNA set against Human ABCA8 (NM_007168.2) - SHH228910 from Creative biogene
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shRNA set against Human ABCA8(NM_007168.2) - SHG023057 from Creative biogene
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ABCA8 shRNA Plasmid (Human) - CHH7017 from Cohesion Biosciences
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ABCA8 miRNA 3'UTR clone - MiUTR1H-00025 from Creative biogene
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