Gene Symbol | PALM |
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Entrez Gene | 5064 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | paralemmin |
Other Description | paralemmin-1 |
Swissprots | Q9UPJ4 Q9UQS2 Q92559 O43359 O95673 O75781 Q9UQS3 |
Accessions | AAC62429 CAA76151 EAW61161 EAW61162 EAW61163 EAW61164 O75781 AK022919 BAG51135 AK299809 BAH13135 AK301181 BAH13424 AK315168 BAG37611 BC019596 BC032449 AAH32449 BM667870 BP199809 BU508077 CN344023 D87460 BAA13400 DA521203 HQ447328 ADQ31814 Y14770 CAB37400 Y16278 CAA76152 XM_005259565 XP_005259622 XM_005259566 XP_005259623 XM_011528043 XP_011526345 XM_011528044 XP_011526346 NM_001040134 NP_001035224 NM_002579 NP_002570 |
Function | Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. {ECO:0000269|PubMed:14978216}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:14978216}; Lipid-anchor {ECO:0000269|PubMed:14978216}; Cytoplasmic side {ECO:0000269|PubMed:14978216}. Cell projection, filopodium membrane {ECO:0000269|PubMed:14978216}; Lipid-anchor {ECO:0000269|PubMed:14978216}. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Basolateral cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Apicolateral cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Translocation to the plasma membrane is enhanced upon stimulation of neuronal activity. |
Tissue Specificity | Widely expressed with highest expression in brain and testis and intermediate expression in heart and adrenal gland. |
Paralemmin (D-5) - sc-365869 from Santa Cruz Biotechnology
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Paralemmin (P-20) - sc-55972 from Santa Cruz Biotechnology
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Paralemmin (T-20) - sc-55974 from Santa Cruz Biotechnology
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Anti-Paralemmin antibody - ab58285 from Abcam
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Anti-Paralemmin antibody - ab108239 from Abcam
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Anti-Paralemmin antibody - ab135173 from Abcam
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Anti-Paralemmin / PALM Antibody (Internal) - LS-C153406 from LifeSpan Bioscience
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Anti-Paralemmin / PALM Antibody (aa35-84) - LS-C117189 from LifeSpan Bioscience
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Anti-Paralemmin / PALM Antibody (clone 7C5) - LS-C133361 from LifeSpan Bioscience
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Paralemmin Antibody - NBP1-87770 from Novus Biologicals
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Paralemmin Antibody - NBP1-79624 from Novus Biologicals
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Paralemmin Antibody (7C5) - H00005064-M09 from Novus Biologicals
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Paralemmin Antibody - H00005064-A01 from Novus Biologicals
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Paralemmin Antibody (4E1.) - H00005064-M06 from Novus Biologicals
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Anti-PALM antibody produced in rabbit - HPA041713 from Sigma-Aldrich
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Monoclonal Anti-PALM antibody produced in mouse - WH0005064M9 from Sigma-Aldrich
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Monoclonal Anti-PALM antibody produced in mouse - SAB1404165 from Sigma-Aldrich
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PALM antibody - N-terminal region (ARP56270_P050) - ARP56270_P050 from Aviva Systems Biology
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PALM-Antibody-monoclonal-M09 - AT3176a from Abgent, a WuXi AppTec company
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PALM antibody - 70R-9381 from Fitzgerald
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PALM antibody - AP31901PU-N from Acris Antibodies
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PALM antibody - H00005064-A01 from Acris Antibodies
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PALM antibody - H00005064-M06 from Acris Antibodies
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PALM antibody - H00005064-M09 from Acris Antibodies
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PALM Antibody - GWB-MU233H from Genway Biotech
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