Gene Symbol | PPM1L |
---|---|
Entrez Gene | 151742 |
Alt Symbol | PP2C-epsilon, PP2CE, PPM1-LIKE |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase, Mg2+/Mn2+ dependent, 1L |
Other Description | PP2C epsilon|Protein phosphatase 2C epsilon isoform|protein phosphatase 1L|protein phosphatase 2C isoform epsilon |
Swissprots | Q96NM7 Q2M3J2 Q5SGD2 |
Accessions | EAW78626 Q5SGD2 AK055115 BAB70856 AK055323 AK055510 AK092378 AY337264 AAR00269 BC035116 BC090872 BC104885 AAI04886 BC104887 AAI04888 BC110801 XM_006713507 XP_006713570 XM_011512440 XP_011510742 XM_011512441 XP_011510743 NM_139245 NP_640338 |
Function | Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. {ECO:0000269|PubMed:17456047}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:15560375}. |
Human PPM1L full length protein - ab165634 from Abcam
|
||||||||||
PPM1L Antibody Blocking Peptide - LS-E658 from LifeSpan Bioscience
|
||||||||||
PPM1L Antibody Blocking Peptide - LS-E24500 from LifeSpan Bioscience
|
||||||||||
Recombinant Human PP2C epsilon/PPM1L Protein - H00151742-P01 from Novus Biologicals
|
||||||||||
PPM1L-Antibody-C-term-Blocking-peptide - BP11001b from Abgent, a WuXi AppTec company
|
||||||||||
Protein phosphatase 1L / PPM1L - H00151742-P01-10 from Acris Antibodies
|
||||||||||
Protein phosphatase 1L / PPM1L - H00151742-P01-25 from Acris Antibodies
|
||||||||||
PPM1L fusion protein - ag12999 from Proteintech Group
|
||||||||||
PPM1L fusion protein - ag12775 from Proteintech Group
|
||||||||||
Recombinant Human Protein phosphatase 1L(PPM1L) - CSB-YP722509HU CSB-EP722509HU CSB-BP722509HU CSB-MP722509HU from Cusabio
|
||||||||||
Protein phosphatase 1L / PPM1L - TP318909 from Acris Antibodies
|
||||||||||
PP2C epsilon/PPM1L Recombinant Protein Antigen - NBP1-87248PEP from Novus Biologicals
|
||||||||||
PP2C epsilon/PPM1L Protein - NBP1-87247PEP from Novus Biologicals
|
||||||||||
PPM1L Peptide, Human - M34GP12221H from Creative Peptides
|