PPM1L

Gene Symbol PPM1L
Entrez Gene 151742
Alt Symbol PP2C-epsilon, PP2CE, PPM1-LIKE
Species Human
Gene Type protein-coding
Description protein phosphatase, Mg2+/Mn2+ dependent, 1L
Other Description PP2C epsilon|Protein phosphatase 2C epsilon isoform|protein phosphatase 1L|protein phosphatase 2C isoform epsilon
Swissprots Q96NM7 Q2M3J2 Q5SGD2
Accessions EAW78626 Q5SGD2 AK055115 BAB70856 AK055323 AK055510 AK092378 AY337264 AAR00269 BC035116 BC090872 BC104885 AAI04886 BC104887 AAI04888 BC110801 XM_006713507 XP_006713570 XM_011512440 XP_011510742 XM_011512441 XP_011510743 NM_139245 NP_640338
Function Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6. {ECO:0000269|PubMed:17456047}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:15560375}.

PP2Cε siRNA (h) - sc-78298 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PP2Cε shRNA Plasmid (h) - sc-78298-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PP2Cε shRNA (h) Lentiviral Particles - sc-78298-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU137701 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0503 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0502 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0504 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17249 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17249 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPM1L siRNA (Human) - CRJ5711 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PP2C epsilon/PPM1L RNAi - H00151742-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PPM1L (NM_139245.2) - SHH380892 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PPM1L(NM_139245.2) - SHR106014 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPM1L siRNA - orb276212 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPM1L shRNA Plasmid (Human) - CHJ5711 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPM1L miRNA 3'UTR clone - MiUTR1H-08168 from Creative biogene

Species Reactivities Human
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