Gene Symbol | CELF3 |
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Entrez Gene | 11189 |
Alt Symbol | BRUNOL1, CAGH4, ERDA4, ETR-1, TNRC4 |
Species | Human |
Gene Type | protein-coding |
Description | CUGBP, Elav-like family member 3 |
Other Description | CAG repeat domain|CAG repeat protein 4|CUG-BP and ETR-3 like factor 3|CUG-BP- and ETR-3-like factor 3|CUGBP Elav-like family member 3|ELAV-type RNA-binding protein 1|RNA-binding protein BRUNOL-1|bruno-like protein 1|expanded repeat domain protein CAG/CTG 4|expanded repeat domain, CAG/CTG 4|trinucleotide repeat containing 4|trinucleotide repeat-containing gene 4 protein |
Swissprots | Q5SZQ8 Q9HB30 O15414 B7ZKK6 Q8IZ98 Q5SZQ7 Q499Y6 Q6NVK0 Q9BZC2 |
Accessions | AAN73886 EAW53419 EAW53420 EAW53421 EAW53422 Q5SZQ8 AB209264 BAD92501 AF284423 AAG14457 AF329264 AAK07474 AK123206 AK298852 BAG60975 AL519587 AY165003 AAN73884 BC004145 AAH04145 BC041088 BC052491 AAH52491 BC068008 AAH68008 BC104758 AAI04759 BC143226 AAI43227 BM680140 DR001924 U80746 AAB91444 U80759 AAB91450 XM_006711139 XP_006711202 XM_006711140 XP_006711203 XM_006711141 XP_006711204 XM_011509111 XP_011507413 XM_011509112 XP_011507414 XM_011509113 XP_011507415 XM_011509114 XP_011507416 NM_001172648 NP_001166119 NM_001172649 NP_001166120 NM_001291106 NP_001278035 NM_001291107 NP_001278036 NM_007185 NP_009116 |
Function | RNA-binding protein involved in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. {ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:15009664}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in brain. {ECO:0000269|PubMed:11158314}. |
CELF3 Antibody Blocking Peptide - LS-E2176 from LifeSpan Bioscience
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CELF3 Antibody Blocking Peptide - LS-E11019 from LifeSpan Bioscience
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TNRC4-Antibody-N-term-Blocking-peptide - BP13087a from Abgent, a WuXi AppTec company
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TNRC4 / BRUNOL1 - H00011189-P01-10 from Acris Antibodies
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TNRC4 / BRUNOL1 - H00011189-P01-25 from Acris Antibodies
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TNRC4 fusion protein - ag18305 from Proteintech Group
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TNRC4 fusion protein - Ag18601 from Proteintech Group
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Recombinant Human CUGBP Elav-like family member 3(CELF3) - CSB-YP732915HU CSB-EP732915HU CSB-BP732915HU CSB-MP732915HU from Cusabio
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TNRC4 / BRUNOL1 - TP308465 from Acris Antibodies
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TNRC4 / BRUNOL1 (transcript variant 3) - TP330039 from Acris Antibodies
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TNRC4 Recombinant Protein Antigen - NBP1-89933PEP from Novus Biologicals
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CELF3 Peptide, Human - M34GP02953H from Creative Peptides
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CUGBP Elav-like family member 3 (CELF3), Recombinant Protein - MBS1386852 from MyBioSource
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