| Gene Symbol | ALDH3A2 |
|---|---|
| Entrez Gene | 224 |
| Alt Symbol | ALDH10, FALDH, SLS |
| Species | Human |
| Gene Type | protein-coding |
| Description | aldehyde dehydrogenase 3 family, member A2 |
| Other Description | aldehyde dehydrogenase 10|aldehyde dehydrogenase family 3 member A2|fatty aldehyde dehydrogenase|microsomal aldehyde dehydrogenase |
| Swissprots | P51648 Q93011 Q6I9T3 Q96J37 |
| Accessions | AAC50965 AAC50966 EAW50898 EAW50899 EAW50900 P51648 AB208894 BAD92131 AK000858 AK025677 AK123877 AK292381 BAF85070 AK315096 BAG37560 BC002430 AAH02430 BG699030 CR457422 CAG33703 CR749559 CAH18356 DQ895880 ABM86806 EU176377 ABW03828 L47162 AAB01003 U46689 AAC51121 XM_011523732 XP_011522034 XM_011523733 XP_011522035 NM_000382 NP_000373 NM_001031806 NP_001026976 |
| Function | Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. {ECO:0000269|PubMed:22633490}. |
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. |
| Top Pathways | Glycolysis / Gluconeogenesis, Tryptophan metabolism, Fatty acid degradation, Pyruvate metabolism, Glycerolipid metabolism |