| Gene Symbol |
SLC36A2
|
| Entrez Gene |
153201
|
| Alt Symbol |
PAT2, TRAMD1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 36 (proton/amino acid symporter), member 2
|
| Other Description |
proton-coupled amino acid transporter 2|tramdorin-1
|
| Swissprots |
Q7Z6B5 Q6ZWK5 Q495M3 Q495M4 Q495M6
|
| Accessions |
EAW61678 Q495M3 AK297682 BAG60042 AK309575 AY162214 AAO11788 AY228364 AAO74832 BC101100 AAI01101 BC101101 AAI01102 BC101102 AAI01103 BC101103 AAI01104 BX538285 DC362112 XM_005268377 XP_005268434 XM_006714756 XP_006714819 XM_011537559 XP_011535861 NM_181776 NP_861441
|
| Function |
Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus. {ECO:0000269|PubMed:15058382, ECO:0000269|PubMed:19033659}.
|