Gene Symbol | SLC36A2 |
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Entrez Gene | 153201 |
Alt Symbol | PAT2, TRAMD1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 36 (proton/amino acid symporter), member 2 |
Other Description | proton-coupled amino acid transporter 2|tramdorin-1 |
Swissprots | Q7Z6B5 Q6ZWK5 Q495M3 Q495M4 Q495M6 |
Accessions | EAW61678 Q495M3 AK297682 BAG60042 AK309575 AY162214 AAO11788 AY228364 AAO74832 BC101100 AAI01101 BC101101 AAI01102 BC101102 AAI01103 BC101103 AAI01104 BX538285 DC362112 XM_005268377 XP_005268434 XM_006714756 XP_006714819 XM_011537559 XP_011535861 NM_181776 NP_861441 |
Function | Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids. Transports glycine and proline. Inhibited by sarcosine (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250}. |
Tissue Specificity | Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus. {ECO:0000269|PubMed:15058382, ECO:0000269|PubMed:19033659}. |
PAT2 CRISPR/Cas9 KO Plasmid (h) - sc-414728 from Santa Cruz Biotechnology
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PAT2 HDR Plasmid (h) - sc-414728-HDR from Santa Cruz Biotechnology
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PAT2 Double Nickase Plasmid (h) - sc-414728-NIC from Santa Cruz Biotechnology
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PAT2 Double Nickase Plasmid (h2) - sc-414728-NIC-2 from Santa Cruz Biotechnology
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PAT2 CRISPR Activation Plasmid (h) - sc-414728-ACT from Santa Cruz Biotechnology
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PAT2 CRISPR Activation Plasmid (h2) - sc-414728-ACT-2 from Santa Cruz Biotechnology
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PAT2 Lentiviral Activation Particles (h) - sc-414728-LAC from Santa Cruz Biotechnology
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PAT2 Lentiviral Activation Particles (h2) - sc-414728-LAC-2 from Santa Cruz Biotechnology
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PAT2 siRNA (h) - sc-91668 from Santa Cruz Biotechnology
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PAT2 shRNA Plasmid (h) - sc-91668-SH from Santa Cruz Biotechnology
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PAT2 shRNA (h) Lentiviral Particles - sc-91668-V from Santa Cruz Biotechnology
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SLC36A2 RNAi - H00153201-R01 from Novus Biologicals
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MISSION® esiRNA - EHU039551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19597 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19597 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12758 from Sigma-Aldrich
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SLC36A2 siRNA (Human) - CRJ5759 from Cohesion Biosciences
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SLC36A2 - MBS8228239 from MyBioSource
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shRNA set against Human Slc36a2 (NM_181776.2) - SHH410840 from Creative biogene
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SLC36A2 shRNA Plasmid (Human) - CHJ5759 from Cohesion Biosciences
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