Gene Symbol | COMT |
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Entrez Gene | 100146509 |
Alt Symbol | - |
Species | Horse |
Gene Type | protein-coding |
Description | catechol-O-methyltransferase |
Other Description | catechol O-methyltransferase|catechol O-methyltransferase, membrane-bound form|catechol O-methyltransferase, soluble form |
Swissprots | Q5H879 Q5H878 |
Accessions | Q5H879 AB178284 BAD89294 NM_001081834 NP_001075303 NM_001114535 NP_001108007 |
Function | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity). {ECO:0000250}. |
Subcellular Location | Isoform 2: Cytoplasm {ECO:0000250}. |
Top Pathways | Steroid hormone biosynthesis, Dopaminergic synapse, Tyrosine metabolism |
Recombinant Horse Catechol O-methyltransferase(COMT) - CSB-YP705158HO CSB-EP705158HO CSB-BP705158HO CSB-MP705158HO from Cusabio
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Catechol O-methyltransferase (COMT), Recombinant Protein - MBS1418145 from MyBioSource
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