Gene Symbol | DECR2 |
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Entrez Gene | 26063 |
Alt Symbol | PDCR, SDR17C1 |
Species | Human |
Gene Type | protein-coding |
Description | 2,4-dienoyl CoA reductase 2, peroxisomal |
Other Description | 2,4-dienoyl-CoA reductase 2|peroxisomal 2,4-dienoyl-CoA reductase|short chain dehydrogenase/reductase family 17C member 1|short chain dehydrogenase/reductase family 17C, member 1 |
Swissprots | Q6ZRS7 Q96ET0 Q9NUI1 |
Accessions | AAK61231 EAW85811 EAW85812 EAW85813 EAW85814 EAW85815 EAW85816 Q9NUI1 AJ293009 CAC05664 AK055839 AK094340 AK128012 BAC87232 AK225961 AL442076 CAC09442 BC010740 AAH10740 BC011968 AAH11968 BC030226 HQ447148 ADQ31635 NM_020664 NP_065715 |
Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Top Pathways | Peroxisome |
DECR2 (8D7) - sc-134312 from Santa Cruz Biotechnology
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DECR2 (G-17) - sc-323779 from Santa Cruz Biotechnology
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DECR2 (L-22) - sc-133507 from Santa Cruz Biotechnology
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DECR2 (T-20) - sc-323780 from Santa Cruz Biotechnology
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Anti-DECR2 antibody - ab153849 from Abcam
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Anti-DECR2 antibody - ab136122 from Abcam
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Anti-DECR2 antibody - ab67591 from Abcam
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Anti-DECR2 Antibody - LS-C307209 from LifeSpan Bioscience
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Anti-DECR2 Antibody (aa49-109) - LS-C307210 from LifeSpan Bioscience
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Anti-DECR2 Antibody - LS-C310118 from LifeSpan Bioscience
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Anti-DECR2 Antibody - LS-C310117 from LifeSpan Bioscience
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Anti-DECR2 Antibody (aa199-248) - LS-C291873 from LifeSpan Bioscience
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Anti-DECR2 Antibody (C-Terminus) - LS-C135133 from LifeSpan Bioscience
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Anti-DECR2 Antibody (aa217-266) - LS-C120194 from LifeSpan Bioscience
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Anti-DECR2 Antibody (N-Terminus) - LS-C80587 from LifeSpan Bioscience
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DECR2 Antibody - NBP1-53172 from Novus Biologicals
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DECR2 Antibody - NBP2-33494 from Novus Biologicals
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DECR2 Antibody - NBP2-16145 from Novus Biologicals
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DECR2 Antibody - H00026063-B01P from Novus Biologicals
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DECR2 Antibody (4A7) - H00026063-M03 from Novus Biologicals
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DECR2 Antibody - H00026063-D01P from Novus Biologicals
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Anti-DECR2, C-Terminal antibody produced in rabbit - SAB4501111 from Sigma-Aldrich
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Anti-DECR2 antibody produced in rabbit - AV43566 from Sigma-Aldrich
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Anti-DECR2 antibody produced in mouse - SAB1407281 from Sigma-Aldrich
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Monoclonal Anti-DECR2 antibody produced in mouse - SAB1402560 from Sigma-Aldrich
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