| Gene Symbol |
DECR2
|
| Entrez Gene |
26063
|
| Alt Symbol |
PDCR, SDR17C1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
2,4-dienoyl CoA reductase 2, peroxisomal
|
| Other Description |
2,4-dienoyl-CoA reductase 2|peroxisomal 2,4-dienoyl-CoA reductase|short chain dehydrogenase/reductase family 17C member 1|short chain dehydrogenase/reductase family 17C, member 1
|
| Swissprots |
Q6ZRS7 Q96ET0 Q9NUI1
|
| Accessions |
AAK61231 EAW85811 EAW85812 EAW85813 EAW85814 EAW85815 EAW85816 Q9NUI1 AJ293009 CAC05664 AK055839 AK094340 AK128012 BAC87232 AK225961 AL442076 CAC09442 BC010740 AAH10740 BC011968 AAH11968 BC030226 HQ447148 ADQ31635 NM_020664 NP_065715
|
| Function |
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
|
| Subcellular Location |
Peroxisome {ECO:0000250}.
|
| Top Pathways |
Peroxisome
|