Gene Symbol | DECR2 |
---|---|
Entrez Gene | 26063 |
Alt Symbol | PDCR, SDR17C1 |
Species | Human |
Gene Type | protein-coding |
Description | 2,4-dienoyl CoA reductase 2, peroxisomal |
Other Description | 2,4-dienoyl-CoA reductase 2|peroxisomal 2,4-dienoyl-CoA reductase|short chain dehydrogenase/reductase family 17C member 1|short chain dehydrogenase/reductase family 17C, member 1 |
Swissprots | Q6ZRS7 Q96ET0 Q9NUI1 |
Accessions | AAK61231 EAW85811 EAW85812 EAW85813 EAW85814 EAW85815 EAW85816 Q9NUI1 AJ293009 CAC05664 AK055839 AK094340 AK128012 BAC87232 AK225961 AL442076 CAC09442 BC010740 AAH10740 BC011968 AAH11968 BC030226 HQ447148 ADQ31635 NM_020664 NP_065715 |
Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Top Pathways | Peroxisome |