Gene Symbol | DECR2 |
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Entrez Gene | 26063 |
Alt Symbol | PDCR, SDR17C1 |
Species | Human |
Gene Type | protein-coding |
Description | 2,4-dienoyl CoA reductase 2, peroxisomal |
Other Description | 2,4-dienoyl-CoA reductase 2|peroxisomal 2,4-dienoyl-CoA reductase|short chain dehydrogenase/reductase family 17C member 1|short chain dehydrogenase/reductase family 17C, member 1 |
Swissprots | Q6ZRS7 Q96ET0 Q9NUI1 |
Accessions | AAK61231 EAW85811 EAW85812 EAW85813 EAW85814 EAW85815 EAW85816 Q9NUI1 AJ293009 CAC05664 AK055839 AK094340 AK128012 BAC87232 AK225961 AL442076 CAC09442 BC010740 AAH10740 BC011968 AAH11968 BC030226 HQ447148 ADQ31635 NM_020664 NP_065715 |
Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
Subcellular Location | Peroxisome {ECO:0000250}. |
Top Pathways | Peroxisome |
Human DECR2 full length protein - ab116178 from Abcam
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DECR2 Antibody Blocking Peptide - LS-E16028 from LifeSpan Bioscience
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DECR2 Antibody Blocking Peptide - LS-E16029 from LifeSpan Bioscience
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DECR2 Partial Recombinant Protein - H00026063-Q01 from Novus Biologicals
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DECR2 Recombinant Protein - H00026063-P01 from Novus Biologicals
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Recombinant Human DECR2 Protein - NBP1-78829 from Novus Biologicals
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Human DECR2 protein - orb168204 from Biorbyt
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DECR2 Blocking Peptide - 33R-5726 from Fitzgerald
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Decr2 Blocking Peptide - 33R-7160 from Fitzgerald
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DECR2 protein (His tag) - 80R-2072 from Fitzgerald
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DECR2 (1-292, His-tag) - AR50155PU-N from Acris Antibodies
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DECR2 (1-292, His-tag) - AR50155PU-S from Acris Antibodies
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DECR2 - H00026063-P01-10 from Acris Antibodies
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DECR2 - H00026063-P01-25 from Acris Antibodies
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DECR2 - H00026063-Q01-10 from Acris Antibodies
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DECR2 - H00026063-Q01-25 from Acris Antibodies
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DECR2, 1-292aa, Human, His tag, E.coli - 01-P1330 from ARP American Research Products
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DECR2 fusion protein - Ag23052 from Proteintech Group
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DECR2 Human - ENPS-218 from NeoScientific
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DECR2, 1-292aa, Recombinant Protein - GWB-P0708F from Genway Biotech
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Recombinant Human 2,4-Dienoyl CoA Reductase 2, Peroxisomal, His-tagged - DECR2-1330H from Creative Biomart
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Recombinant Human DECR2, His-tagged - DECR2-27085TH from Creative Biomart
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DECR2 1-292aa - CMB-1163 from Reagent Proteins
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Recombinant Human Peroxisomal 2,4-dienoyl-CoA reductase(DECR2) - CSB-YP873655HU CSB-EP873655HU CSB-BP873655HU CSB-MP873655HU from Cusabio
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DECR2, 1-292aa, Human, His tag, E.coli - ATGP1330 from ATGen
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